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NBoc-p-anisidine

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Identification
Molecular formula
C14H20N2O4
CAS number
84645-69-8
IUPAC name
[3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate
State
State

At room temperature, NBoc-p-anisidine is a solid. It exists as a crystalline powder and is usually quite stable under normal conditions.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
323.50
Boiling point (Kelvin)
596.65
General information
Molecular weight
265.32g/mol
Molar mass
265.3120g/mol
Density
1.1800g/cm3
Appearence

NBoc-p-anisidine appears as a white to off-white solid powder. It is primarily used as an intermediate in organic synthesis, particularly in the formation of pharmaceuticals and agrochemicals.

Comment on solubility

Solubility of [3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate

The solubility characteristics of [3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate are influenced by its structural components. In general, the solubility of this compound can be examined in various solvents, enhancing our understanding of its behavior in different environments.

Key Solubility Insights:

  • The presence of a methoxy group usually suggests improved solubility in organic solvents, due to both its hydrophobic nature and ability to engage in hydrogen bonding.
  • The carbamate group can enhance solubility in polar solvents like water, but the steric hindrance from the tert-butyl substituent may complicate this behavior.
  • In general, compounds containing both polar and non-polar characteristics tend to be soluble in a range of solvents, indicating a degree of amphiphilicity.

It’s important to note that factors such as temperature and the presence of other solutes can also significantly affect solubility. As a rule of thumb, when investigating solubility, consider the “like dissolves like” principle, where polar solutes tend to dissolve in polar solvents, and non-polar solutes in non-polar solvents.

In conclusion, while [3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate may demonstrate varied solubility profiles, future empirical studies will provide comprehensive insights into its solubility behavior in both aqueous and organic environments.

Interesting facts

Exploring [3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate

[3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate is a fascinating compound that resides at the intersection of organic chemistry and pharmaceuticals. This compound showcases the versatility of carbamate derivatives, which are integral in drug design and synthesis. Here are some compelling facts about this intriguing molecule:

  • Medicinal Applications: Carbamates like this compound are often studied for their potential use in therapeutics, including anti-cancer and anti-inflammatory treatments.
  • Synthetic Flexibility: The unique structure of [3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate allows for various synthetic routes, enabling chemists to explore multiple methodologies for its preparation.
  • Importance in Agrochemicals: Beyond pharmaceuticals, carbamate derivatives are also essential in the formulation of pesticides and herbicides, aiding in crop protection.
  • Link to Amino Acids: The presence of the amino group in its structure connects this compound to essential biological scaffolds, highlighting its potential biological reactivity.

Furthermore, compounds of this nature often serve as key intermediates in the synthesis of other complex molecules. As stated in the words of a prominent chemist, "The beauty of organic chemistry lies in the ability to take simple building blocks and create sophisticated architectures."

This compound exemplifies that principle, offering endless opportunities for exploration and innovation within the field. As researchers continue to delve into its properties and reactions, the future promises exciting potential for advancements in both science and industry.

Synonyms
13792-82-0
CARBANILIC ACID, m-HYDROXY-, METHYL ESTER, tert-BUTYLCARBAMATE (ester)
Methyl m-hydroxycarbanilate, tert-butylcarbamate
BRN 2419573
DTXSID20160397
DTXCID8082888
[3-(methoxycarbonylamino)phenyl] N-tert-butylcarbamate
m-(tert-Butylcarbamoyloxy)carbanilic acid methyl ester