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3-Methoxydibenzofuran-2-amine

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Identification
Molecular formula
C13H11NO2
CAS number
57823-61-9
IUPAC name
3-methoxydibenzofuran-2-amine
State
State

At room temperature, 3-methoxydibenzofuran-2-amine is typically in the solid state. It is stable under normal conditions but should be stored in airtight containers to avoid moisture absorption or degradation.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.00
Boiling point (Celsius)
389.00
Boiling point (Kelvin)
662.00
General information
Molecular weight
213.24g/mol
Molar mass
213.2430g/mol
Density
1.2040g/cm3
Appearence

3-Methoxydibenzofuran-2-amine typically appears as an off-white to pale yellow crystalline powder. The compound is solid under standard conditions and exhibits noticeable aromaticity in its structure due to the presence of the dibenzofuran moiety.

Comment on solubility

Solubility of 3-methoxydibenzofuran-2-amine

The solubility of 3-methoxydibenzofuran-2-amine presents a fascinating exploration into its chemical behavior, which is influenced by various factors. Understanding its solubility properties is essential for both practical applications and theoretical studies.

  • Polar and Non-Polar Character: The presence of the methoxy group introduces some polarity, which may enhance solubility in polar solvents. Conversely, the dibenzofuran backbone contributes to a more hydrophobic character, impacting solubility in water.
  • Solvents: 3-methoxydibenzofuran-2-amine is likely to be more soluble in organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Methanol
    • Acetone
  • Influence of Temperature: As with many organic compounds, an increase in temperature typically enhances solubility due to increased kinetic energy and disruption of intermolecular interactions.
  • pH Dependence: The solubility could also be affected by the pH of the solution, particularly if the amine behaves as a proton acceptor, possibly forming soluble salt forms in acidic environments.

In conclusion, the solubility behavior of 3-methoxydibenzofuran-2-amine is characterized by a complex interaction of its molecular structure with the solvent environment, reinforcing the importance of considering both functional groups and the surrounding conditions.

Interesting facts

Interesting Facts about 3-Methoxydibenzofuran-2-amine

3-Methoxydibenzofuran-2-amine is a fascinating compound that has intrigued many in the fields of medicinal chemistry and organic synthesis. Below are some key highlights that showcase its significance:

  • Structural Complexity: This compound features a unique structure combining a dibenzofuran moiety with an amine group. This complexity opens avenues for creating derivatives that can exhibit varied biological activities.
  • Potential Biological Activity: Compounds containing dibenzofuran skeletons have been investigated for their pharmacological properties, including anti-inflammatory and antiallergic activities. This could suggest a potential therapeutic role for 3-methoxydibenzofuran-2-amine in modern medicine.
  • Research Applications: Due to its structure, it can serve as a vital lead compound in drug discovery. Researchers often explore compounds like this aimed at developing new treatments for various diseases.
  • Role in Organic Synthesis: 3-Methoxydibenzofuran-2-amine can be used as a building block in organic synthesis for the creation of more complex organic molecules. Its reactivity patterns are of interest to synthetic chemists.
  • Environmental Importance: Some studies suggest that derivatives of dibenzofuran may possess properties that influence ecological factors, underscoring the importance of understanding their environmental impact.

As with many chemical compounds, the exploration of 3-methoxydibenzofuran-2-amine is a journey of discovery. As one scientist noted, "Each molecule tells a story of its interactions and potentials, waiting to be unfolded." Therefore, it remains a captivating subject of study in both academic and practical applications.

Synonyms
3-Methoxy-2-dibenzofuranamine
3-methoxydibenzofuran-2-amine
951-39-3
2-Amino-3-methoxydiphenylene oxide
3-Methoxy-2-aminodiphenylene oxide
2-DIBENZOFURANAMINE, 3-METHOXY-
UNII-R4512CL235
R4512CL235
DTXSID40241753
DTXCID70164244
3-methoxydibenzo[b,d]furan-2-amine
SCHEMBL1178016
STL455118
Q27287776