Skip to main content

Guaiacol

ADVERTISEMENT
Identification
Molecular formula
C7H8O2
CAS number
90-05-1
IUPAC name
3-methoxyphenol
State
State

At room temperature, guaiacol is a liquid.

Melting point (Celsius)
28.00
Melting point (Kelvin)
301.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
124.14g/mol
Molar mass
124.1380g/mol
Density
1.1290g/cm3
Appearence

Guaiacol appears as a colorless to pale yellow aromatic oil. It has a distinct odor reminiscent of smoke, which is often associated with the aroma of creosote or other phenolic compounds.

Comment on solubility

Solubility of 3-Methoxyphenol

3-Methoxyphenol, also known as guaiacol, is a compound with notable solubility characteristics. Its solubility can be described as follows:

  • Water Solubility: 3-Methoxyphenol displays moderate solubility in water. At room temperature, it can dissolve to a certain extent, but its effectiveness in forming solutions can be affected by factors such as temperature and pH.
  • Solubility in Organic Solvents: This compound is highly soluble in organic solvents. Some of these include:
    • Ethyl acetate
    • Ethanol
    • Acetone
  • Effect of Temperature: Increasing temperature can enhance solubility, allowing for greater amounts of 3-methoxyphenol to dissolve in both water and organic solvents.

In summary, while 3-methoxyphenol shows moderate solubility in water, its ability to dissolve in a variety of organic solvents makes it a versatile compound for various applications. Its solubility characteristics significantly influence its behavior and reactivity in different chemical environments.

Interesting facts

Interesting Facts about 3-Methoxyphenol

3-Methoxyphenol, commonly known as guaiacol, is a fascinating compound with a rich history and diverse applications. Below are several intriguing aspects of this aromatic molecule:

  • Natural Origins: Guaiacol can be derived from natural sources, particularly from the wood of certain trees and as a by-product of lignin breakdown. It is often found in smoke, leading to its association with flavors like those found in smoked meats.
  • Flavor & Aroma: Due to its sweet, smoky, and somewhat spicy aroma, guaiacol is used in the flavoring industry. It is a common ingredient in products designed to impart a “smoked” flavor.
  • Medicinal Uses: Guaiacol exhibits notable antiseptic properties, making it useful in some medicinal applications, particularly as a cough suppressant and an expectorant in pharmaceutical products.
  • Industrial Applications: This compound serves as an important precursor in the synthesis of various chemical compounds including the production of phenolic compounds and synthetic resins.
  • Research Applications: In the realm of chemistry, guaiacol is utilized in research to study reaction mechanisms and serves as a model compound for investigating the behavior of phenolic compounds under different conditions.

In summary, 3-methoxyphenol is not just a simple molecule; it is a compound with significance in food science, medicine, and industrial chemistry. Its versatility and natural origins make it a noteworthy topic in the study of organic compounds!

Synonyms
3-METHOXYPHENOL
150-19-6
m-Methoxyphenol
3-Hydroxyanisole
Phenol, 3-methoxy-
m-Hydroxyanisole
m-Guaiacol
Resorcinol monomethyl ether
1-Hydroxy-3-methoxybenzene
Resorcinol methyl ether
Phenol, m-methoxy-
3-(methyloxy)phenol
m-Hydroxyanisol
3-METHOXY-PHENOL
EINECS 205-754-6
MFCD00002267
NSC 21735
UNII-HXB7441U87
DTXSID0022012
CHEBI:52678
ORISTAR HOA
AI3-00796
NSC-21735
DTXCID302012
HXB7441U87
3-methoxy phenol
3-Hydroxyanisol
mHydroxyanisole
mMethoxyphenol
mGuaiacol
Guaiacol Imp. H (EP); 3-Methoxyphenol; Guaiacol Impurity H
3Hydroxyanisole
m-methoxy-phenol
3-methoxy-pheno
Phenol, mmethoxy
3-methyloxyphenol
Phenol, 3methoxy
1Hydroxy3methoxybenzene
3-Methoxyphenol, 96%
3-Methoxyphenol - 98%
3-Methoxyphenol (Standard)
SCHEMBL28256
CHEMBL57891
M-HYDROXYANISOLE [INCI]
SCHEMBL12015261
BDBM36297
HY-Y1840R
CS-D1677
HY-Y1840
NSC21735
3-Methoxyphenol, analytical standard
Tox21_303820
CK1184
STL141067
AKOS000120300
FM25316
NCGC00357098-01
AC-18515
AS-45839
CAS-150-19-6
PD207030
DB-002515
M0122
NS00020150
EN300-20543
Q27123546
F0001-0533
Z104478798
1-Hydroxy-3-methoxybenzene;3-Hydroxyanisole;Resorcinol monomethyl ether;m-Hydroxyanisole