3-Methyl-1-phenylisothiourea | Solubility of Things

Identification

Molecular formula

C₉H₁₂N₂S

CAS number

496-94-6

IUPAC name

3-methyl-1-phenyl-isothiourea

State

At room temperature, 3-methyl-1-phenylisothiourea is in a solid state. It is typically stable under standard conditions and maintains its structural integrity in air.

Melting point (Celsius)

121.50

Melting point (Kelvin)

394.65

Boiling point (Celsius)

402.00

Boiling point (Kelvin)

675.15

General information

Molecular weight

179.27g/mol

Molar mass

179.2700g/mol

Density

1.2810g/cm³

Appearence

3-Methyl-1-phenylisothiourea appears as a white crystalline solid. The compound typically exists in a pure state and should appear free from impurities, maintaining a consistent opaque white coloration.

Comment on solubility

Solubility of 3-methyl-1-phenyl-isothiourea

The solubility of 3-methyl-1-phenyl-isothiourea, a compound with the chemical formula C₁₀H₁₂N₂S, presents intriguing characteristics influenced by its unique molecular structure. This compound tends to exhibit the following solubility profile:

Water Solubility: Generally, isothiourea derivatives like this one can have limited solubility in water due to their hydrophobic aromatic ring.
Organic Solvents: It often shows better solubility in organic solvents such as ethanol or methanol, which can solvate the non-polar regions of the molecule effectively.

It's important to note that the solubility can be affected by factors such as temperature and the presence of other solutes. The **hydrophilicity** or **hydrophobicity** of the isothiourea group plays a pivotal role in how this compound interacts with solvents. As researchers have noted, "the solubility properties can have significant implications in various applications, including pharmaceuticals and material sciences." Therefore, understanding and manipulating the solubility of 3-methyl-1-phenyl-isothiourea can enhance its utility in chemical syntheses and formulations.

Interesting facts

Interesting Facts about 3-Methyl-1-phenyl-isothiourea

3-Methyl-1-phenyl-isothiourea is a fascinating compound that presents a unique structure and a variety of applications in the field of chemistry. Here are some intriguing points about this versatile molecule:

Structural Characteristics: This compound is part of the isothiourea family, which features a sulfur atom bonded to a carbon and a nitrogen atom. Its distinctive arrangement contributes to its reactivity and interaction with other chemicals.
Biological Relevance: Research has shown that isothioureas, including 3-methyl-1-phenyl-isothiourea, can act as inhibitors for certain enzymes. For example, they have demonstrated potential in inhibiting nitric oxide synthase (NOS), making them of interest for medicinal chemistry.
Research Applications: This compound has been studied for its role in various biological processes and its potential therapeutic applications, particularly in cancer research and pharmacology.
Analytical Use: Due to its reactive nature, 3-methyl-1-phenyl-isothiourea is also employed in analytical chemistry as a reagent, providing insights into the behavior of other chemical species.
Fun Fact: Isothioureas are known for their ability to serve as intermediates in the synthesis of a variety of nitrogen-containing compounds, showcasing the compound's role in the broader context of organic synthesis.

In summary, 3-methyl-1-phenyl-isothiourea is not just a simple compound; it embodies a diverse range of chemical properties and potential applications that intrigue researchers across multiple disciplines. Its unique characteristics and interactions with biological systems make it a compelling subject of study.