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3-Methylquinoxalin-2(1H)-one

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Identification
Molecular formula
C9H8N2O
CAS number
6940-78-9
IUPAC name
3-methyl-1H-quinoxalin-2-one
State
State

At room temperature, 3-Methylquinoxalin-2-one is in a solid state. It is stable under normal conditions and does not exhibit volatility or fluidity due to its crystalline nature.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
160.17g/mol
Molar mass
160.1740g/mol
Density
1.2480g/cm3
Appearence

3-Methylquinoxalin-2-one is a crystalline solid that often appears as off-white or pale yellow in color. Its crystalline structure allows it to reflect light, giving it a slight sheen when observed under proper lighting conditions. It is typically found in powder form.

Comment on solubility

Solubility of 3-methyl-1H-quinoxalin-2-one

The solubility of 3-methyl-1H-quinoxalin-2-one can be influenced by various factors including temperature, solvent polarity, and molecular interactions. Here are key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol due to its aromatic nature.
  • Water Solubility: Its solubility in water is quite limited; it exhibits low to moderate solubility depending on specific conditions.
  • Temperature Effects: Increasing temperature may enhance solubility in some solvents, which is a common phenomenon for many organic compounds.
  • pH Influence: The solubility can also be affected by pH, potentially increasing in acidic or basic conditions depending on the nature of any functional groups present.

In summary, while 3-methyl-1H-quinoxalin-2-one demonstrates notable solubility in certain organic solvents, its poor solubility in water highlights its characteristic behavior as a hydrophobic compound. Always consider the solvent system and environmental conditions when assessing solubility. As the saying goes, "like dissolves like," which rings true in the context of this compound's solubility profile.

Interesting facts

Interesting Facts About 3-Methyl-1H-Quinoxalin-2-One

3-Methyl-1H-quinoxalin-2-one is an intriguing compound that belongs to the class of quinoxalines, which are bicyclic compounds featuring a fused benzene and pyridine ring.

Unique Characteristics

  • Bioactivity: This compound exhibits notable bioactive properties, making it of interest in pharmaceutical research. It has been studied for its potential applications in treating various diseases, particularly due to its unique structural features.
  • Interdisciplinary Applications: Researchers have explored its use across various fields, including pharmacology, organic chemistry, and material sciences, demonstrating its versatility.
  • Heterocycles: As a member of the heterocyclic family, 3-methyl-1H-quinoxalin-2-one contributes to a vast number of studies focusing on organic compounds containing rings of atoms, enhancing our understanding of complex molecular frameworks.

Potential Impacts

The study of 3-methyl-1H-quinoxalin-2-one opens up avenues for:

  • Investigating antimicrobial and antitumor properties that may lead to the development of new therapeutic agents.
  • Designing functional materials that leverage its chemical reactivity and stability for applications in electronics and dyes.
  • Enhancing our understanding of quinoxaline derivatives and their importance in medicinal chemistry.

Recent Discoveries

Recent studies have highlighted new synthetic routes and methodologies to create derivatives of 3-methyl-1H-quinoxalin-2-one. For example, researchers have explored:

  • Novel reactions that allow for better yield and purity of the compound.
  • Mechanisms of action when interacting with biological systems, paving the way for future drug development.

Overall, 3-methyl-1H-quinoxalin-2-one exemplifies the dynamic relationship between chemistry and its real-world applications, showcasing how even a single compound can be the key to significant scientific advancements.

Synonyms
3-Methylquinoxalin-2-ol
3-Methyl-2(1H)-quinoxalinone
237-807-4
14003-34-0
2-Hydroxy-3-methylquinoxaline
3-Methyl-1H-quinoxalin-2-one
3-Methyl-2-quinoxalinol
2(1H)-Quinoxalinone, 3-methyl-
3-methylquinoxalin-2(1H)-one
2-QUINOXALINOL, 3-METHYL-
USAF EL-7
3-methyl-1,2-dihydroquinoxalin-2-one
3-methyl-2-Quinoxalinone
MFCD00047567
NSC-149824
WLN: T66 BN ENJ CQ D
3-Hydroxy-2-methylquinoxaline
2-Hydroxy-3-methyl quinoxaline
EINECS 237-807-4
NSC 149824
NSC38589
3-Methyl-2-quinoxalone
3-methyl-quinoxalin-2-ol
MLS000778411
3-methylhydroquinoxalin-2-one
SCHEMBL536562
CHEMBL157238
SCHEMBL1589916
SCHEMBL16403339
SCHEMBL28095819
SCHEMBL28228457
SCHEMBL30617972
DTXSID30161219
CHEBI:167821
5776PWB76Y
HMS2774P17
quinoxaline, 2-hydroxy-3-methyl-
ALBB-020076
CCG-1920
NSC17798
CCG-49309
NSC-17798
NSC-38589
NSC149824
SBB003967
STK874234
STL138586
AKOS000120338
AKOS000446145
FM36074
MF-0223
NCGC00246411-01
CS-10790
PD021324
SMR000415205
SY036050
DB-042505
CS-0065942
NS00015315
ST45022914
EN300-18172
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N
G68962
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.1
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.2
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.3
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.4
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.5
10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.7
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.1
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.2
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.3
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.4
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.5
doi:10.14272/BMIMNRPAEPIYDN-UHFFFAOYSA-N.7
SR-01000638772-1
Z57254350
F0176-0156
InChI=1/C9H8N2O/c1-6-9(12)11-8-5-3-2-4-7(8)10-6/h2-5H,1H3,(H,11,12