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3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile

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Identification
Molecular formula
C23H30N2
CAS number
92382-83-7
IUPAC name
3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile
State
State

At room temperature, 3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile is in a liquid state.

Melting point (Celsius)
-45.10
Melting point (Kelvin)
228.05
Boiling point (Celsius)
343.00
Boiling point (Kelvin)
616.15
General information
Molecular weight
331.49g/mol
Molar mass
331.4860g/mol
Density
1.0125g/cm3
Appearence

3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile is typically a colorless to pale yellow liquid. It is known for having a strong, sharp odor characteristic of many nitriles.

Comment on solubility

Solubility of 3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile

The solubility of 3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile can be understood by considering various factors.

Key Points Regarding Solubility:

  • The presence of a nitrile functional group typically suggests polar characteristics, which might facilitate solubility in polar solvents.
  • Given its aromatic components, such as the 1-naphthyl group, hydrophobic interactions may play a significant role in its overall solubility profile.
  • Additionally, the presence of the piperidyl moiety introduces a potential for hydrogen bonding, which may enhance solubility in polar environments.

However, as the structure is complex, the overall balance between these polar and non-polar characteristics leads to:

  • High solubility in organic solvents, such as ethanol, methanol, and dichloromethane.
  • Limited solubility in water, which could be attributed to its significant hydrophobic regions.

In summary, while 3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile shows promising solubility in non-polar and polar organic solvents, its solubility in aqueous environments is less favorable, a typical trait for compounds with similar structural features.

Interesting facts

Interesting Facts about 3-methyl-2-(1-naphthyl)-2-[2-(1-piperidyl)ethyl]pentanenitrile

This compound belongs to a class of chemicals that are often explored for their potential applications in medicinal chemistry and pharmacology. Here are several noteworthy aspects of this intriguing compound:

  • Complex Structure: The molecular structure features a unique combination of a naphthalene ring and a piperidine moiety, both of which are known for significant biological activities. Such structural diversity often leads to interesting pharmacological properties.
  • Potential Drug Candidates: Compounds with similar structures are frequently investigated for their ability to act as receptor modulators, particularly in the realm of central nervous system (CNS) effects.
  • Research Relevance: This compound may serve as a valuable reference in research focusing on the development of new therapeutic agents, especially those aimed at treating neurological disorders.
  • Chirality Considerations: Depending on the stereochemistry, variations of this compound could exhibit different biological activities, which is crucial for drug design and efficacy. Chirality plays a vital role in the interactions of these compounds with biological systems.
  • Draws from Natural Products: The naphthalene component of the structure is a scaffold derived from natural sources, showcasing how nature can inspire synthetic chemistry.

As you delve deeper into the study of this compound, consider the relationships between different structural components and their resulting biological activities. This could provide valuable insights into the design of the next generation of pharmaceuticals.

Synonyms
1241-64-1
BRN 1352951
alpha-sec-Butyl-alpha-(2-piperidinoethyl)-1-naphthaleneacetonitrile
5-20-03-00086 (Beilstein Handbook Reference)
1-NAPHTHALENEACETONITRILE, alpha-sec-BUTYL-alpha-(2-PIPERIDINOETHYL)-
3-methyl-2-naphthalen-1-yl-2-(2-piperidin-1-ylethyl)pentanenitrile
alpha-(1-Methylpropyl)-alpha-(2-piperidinoethyl)-1-naphthaleneacetonitrile
DTXSID60924733
3-methyl-2-(naphthalen-1-yl)-2-[2-(piperidin-1-yl)ethyl]pentanenitrile
3-methyl-2-naphthalen-1-yl-2-(2-piperidin-1-ylethyl) pentanenitrile