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Flecainide

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Identification
Molecular formula
C20H26F2N2O3
CAS number
54143-55-4
IUPAC name
3-methyl-2-(2-morpholinoethyl)-2-(1-naphthyl)pentanenitrile
State
State

Flecainide is typically found in a solid state at room temperature.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
372.50
Boiling point (Kelvin)
645.65
General information
Molecular weight
427.55g/mol
Molar mass
427.5460g/mol
Density
1.4641g/cm3
Appearence

Flecainide appears as a white to slightly off-white crystalline powder. It is very slightly soluble in water, soluble in methanol, and slightly soluble in ethanol.

Comment on solubility

Solubility of 3-methyl-2-(2-morpholinoethyl)-2-(1-naphthyl)pentanenitrile

The solubility of 3-methyl-2-(2-morpholinoethyl)-2-(1-naphthyl)pentanenitrile is influenced by a variety of factors due to its complex molecular structure. This compound, with its unique functional groups, presents interesting solubility characteristics:

  • Polarity: The presence of the morpholine and naphthyl groups contribute to both polar and nonpolar characteristics, which can affect solubility in different solvents.
  • Solvent Interaction: It is likely to exhibit better solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) due to its relatively large nonpolar structure compared to polar solvents.
  • Hydrogen Bonding: The morpholine moiety can participate in hydrogen bonding, enhancing solubility in polar solvents while possibly limiting solubility in less polar ones.

In practical terms, it's essential to consider the following when assessing solubility:

  1. **Temperature:** Increasing temperature often increases solubility, so testing at various temperatures may yield different results.
  2. **pH Levels:** Depending on the ionization of the morpholine group, changes in pH could affect solubility in aqueous solutions.
  3. **Concentration:** The saturation point can vary, thus requiring careful observation during solute preparation.

Overall, while solubility information for this specific compound may not be widely documented, understanding the underlying chemical properties allows us to make educated assumptions about how it might behave in various solvents.

Interesting facts

Interesting Facts about 3-Methyl-2-(2-morpholinoethyl)-2-(1-naphthyl)pentanenitrile

This intriguing compound belongs to the class of nitriles, which are known for their unique reactivity and functional versatility in organic chemistry. With a complex structure featuring a naphthyl group and morpholine moiety, this compound showcases how functional groups can influence the properties and behaviors of a molecule.

Key Highlights:

  • Pharmacological Potential: Compounds with similar structures often exhibit interesting biological activity, making them candidates for further research in pharmaceuticals.
  • Synthesis Challenges: The synthesis of such complex molecules typically presents interesting challenges for chemists, requiring precise reaction conditions and techniques.
  • Structure-Activity Relationship (SAR): The presence of both a morpholine ring and a naphthyl group allows for extensive exploration of SAR, which is crucial in drug discovery processes.
  • Industrial Applications: Nitriles are widely used in the production of various industrial chemicals, and understanding the properties of this compound could lead to innovative applications.

As a fascinating subject of study, 3-methyl-2-(2-morpholinoethyl)-2-(1-naphthyl)pentanenitrile serves as a prime example of how structural complexity can pave the way for advancing scientific knowledge and potential innovations in the field of chemistry.

In the words of a famous chemist, "Chemistry is the study of transformation, and each compound tells a unique story." This compound is no exception, offering numerous pathways for exploration and discovery.

Synonyms
1241-65-2
BRN 1087846
alpha-sec-Butyl-alpha-(2-morpholinoethyl)-1-naphthaleneacetonitrile
1-NAPHTHALENEACETONITRILE, alpha-sec-BUTYL-alpha-(2-MORPHOLINOETHYL)-
3-methyl-2-(2-morpholin-4-ylethyl)-2-naphthalen-1-ylpentanenitrile
alpha-(1-Methylpropyl)-alpha-(2-morpholinoethyl)-1-naphthaleneacetonitrile
DTXSID20924734
3-METHYL-2-[2-(MORPHOLIN-4-YL)ETHYL]-2-(NAPHTHALEN-1-YL)PENTANENITRILE