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Thioflavin T

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Identification
Molecular formula
C17H19N2S2Cl
CAS number
2390-54-7
IUPAC name
3-methyl-2-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,3-benzothiazole
State
State

At room temperature, Thioflavin T is a solid, typically handled in its crystalline powder form.

Melting point (Celsius)
189.50
Melting point (Kelvin)
462.70
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
318.44g/mol
Molar mass
318.4410g/mol
Density
1.1050g/cm3
Appearence

Thioflavin T appears as a yellow crystalline powder. It is often used in solution form for various microscopy and fluorescence applications, where it fluoresces intensively under UV light.

Comment on solubility

Solubility of 3-methyl-2-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,3-benzothiazole

The solubility of 3-methyl-2-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,3-benzothiazole is influenced by several factors, including its molecular structure and the presence of functional groups. Understanding its solubility is crucial for applications in fields such as pharmaceuticals and materials science. Here are key points regarding its solubility:

  • Polar vs. Non-Polar: Given its complex aromatic structure, this compound is generally expected to exhibit limited solubility in water but may dissolve in organic solvents like DMSO or ethanol.
  • Ionization: The presence of the quaternary ammonium group may enhance solubility in polar solvents due to the ion-dipole interactions.
  • Temperature Dependence: Solubility could increase with temperature, as is typical for many organic compounds.
  • pH Sensitivity: Depending on the pH of the solution, the ionic form of the molecule might affect its solubility.

As a rule of thumb, like dissolves like; thus, non-polar compounds are more soluble in non-polar solvents while polar compounds are soluble in polar solvents. Understanding the nuances of solubility can lead to better applications and formulations in various scientific endeavors.

Interesting facts

Interesting Facts About 3-Methyl-2-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,3-benzothiazole

This compound, a fascinating member of the benzothiazole family, showcases intriguing structural features and potential applications in various fields. Here are some noteworthy aspects:

  • Structural Complexity: The compound features a unique combination of methyl groups and a methylene bridge that connects two distinct benzothiazole moieties. This structural elegance contributes to its chemical reactivity and function.
  • Biological Interest: Compounds like this one are known for their biological activity, making them subjects of study in medicinal chemistry. The benzothiazole scaffold is often explored for its potential in developing therapeutic agents against diseases.
  • Fluorescent Properties: Many derivatives of benzothiazole exhibit fluorescence, which can be harnessed in imaging techniques and biosensors. The fluorescent properties can provide insight into molecular interactions in biological systems.
  • Environmental Relevance: Research is ongoing on the role of benzothiazole derivatives in environmental chemistry, especially regarding their persistence and degrading mechanisms in ecosystems.
  • Versatile Applications: Beyond biology, compounds of this class are increasingly used in materials science. Their semi-conductive and optical properties make them suitable for applications in organic electronics and photonic devices.

To quote a renowned chemist, "The beauty of chemistry lies in the connections, both molecular and practical, that we can forge through understanding structures like those found in benzothiazoles." With ongoing research unveiling new potential uses for compounds like 3-methyl-2-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,3-benzothiazole, the future of this compound looks promising.

Synonyms
SCHEMBL12039978