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Bupropion

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Identification
Molecular formula
C13H18ClNO•HCl
CAS number
34911-55-2
IUPAC name
3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile
State
State
The compound is usually in a solid state at room temperature, often found as a powder or within tablet formulations.
Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
274.80
Boiling point (Kelvin)
547.95
General information
Molecular weight
239.75g/mol
Molar mass
239.7530g/mol
Density
1.1000g/cm3
Appearence

Bupropion is typically observed as a white, crystalline powder. It is slightly soluble in water, with varying solubility in different organic solvents. The appearance may sometimes vary based on the formulation and presentation for pharmaceutical uses.

Comment on solubility

Solubility of 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile

The solubility of 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile can be quite complex due to its unique molecular structure. Understanding its solubility can be approached by considering several important factors:

  • Polarity: The presence of the nitrile group (-C≡N) in the compound introduces a polar functional group, which can enhance solubility in polar solvents.
  • Functional Groups: The compound features both hydrophobic (aromatic rings and alkyl chains) and hydrophilic (nitrile and piperidine) regions, affecting its solubility profile.
  • Solvent Type: Typically, this compound is expected to have better solubility in organic solvents such as ethanol or acetone, while its solubility in water may be limited due to the bulky hydrocarbon structure.
  • Temperature Influence: Increased temperatures may enhance solubility for certain organic compounds, potentially allowing better dissolution rates.

In summary, while specific solubility data can vary, 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile is likely to demonstrate varied solubility characteristics. As mentioned, the compound's balance between hydrophobic and hydrophilic features plays a crucial role in defining how well it dissolves in different media.

Interesting facts

Interesting Facts about 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile

This compound, known as 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile, belongs to a class of organic compounds that have garnered attention for their potential applications in medicinal chemistry.

Key Features

  • Structural Complexity: The presence of both a piperidine and a nitrile functional group adds significant complexity to the structure, making it a fascinating subject for study in organic synthesis.
  • Pharmacological Potential: Molecules featuring piperidine rings are often investigated for their abilities to modulate neurotransmitter systems, suggesting that this compound could play a role in targeting neurological pathways.
  • Homologous Series: This compound is a member of a homologous series, which allows chemists to explore variations in biological activity by altering the side groups.
  • Synthetic Applications: The synthesis of such compounds exemplifies important methodologies in drug discovery, especially in the context of designing compounds with targeted bioactivity.

Applications in Research

Research on 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile might involve:

  • Investigating its interactions with specific receptors in the brain.
  • Exploring its efficacy as a potential therapeutic agent in various neurological disorders.
  • Understanding its mechanism of action at the molecular level.

Quote from Experts

As noted by leading researchers in medicinal chemistry, “The intricate design of organic molecules can lead to groundbreaking advancements in pharmaceuticals and therapeutics.” This statement reflects the heart of why compounds like 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile are so significant in ongoing scientific research.

In conclusion, compounds such as 3-methyl-2-phenyl-2-[2-(1-piperidyl)ethyl]butanenitrile exemplify the interplay between complex chemistry and realistic therapeutic applications. Their study not only enriches our understanding of organic chemistry but also opens the door to potential treatments for neurological conditions.

Synonyms
2809-50-9
BRN 1348599
2-Phenyl-2-(2-piperidinoethyl)-3-methylbutyronitrile
BUTYRONITRILE, 2-PHENYL-2-(2-PIPERIDINOETHYL)-3-METHYL-
5-20-03-00077 (beilstein handbook reference)
DTXSID90950823
2-PHENYL-2-(2-PIPERIDIN-1-YLETHYL)-3-METHYLBUTANENITRILE
3-METHYL-2-PHENYL-2-[2-(PIPERIDIN-1-YL)ETHYL]BUTANENITRILE