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3-Methyl-2-phenylbutanoic acid

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Identification
Molecular formula
C11H14O2
CAS number
22746-32-3
IUPAC name
3-methyl-2-phenyl-butanoic acid
State
State

At room temperature, 3-Methyl-2-phenylbutanoic acid is typically a solid. It is stable at room temperature but may need to be handled with care to prevent its sublimation or melting when exposed to higher temperatures.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.15
Boiling point (Celsius)
275.30
Boiling point (Kelvin)
548.45
General information
Molecular weight
178.24g/mol
Molar mass
178.2380g/mol
Density
1.0074g/cm3
Appearence

3-Methyl-2-phenylbutanoic acid typically appears as a white crystalline solid. The crystals are fine and can be powdery. It has a distinctive smell and is usually stored in airtight containers to preserve its chemical stability.

Comment on solubility

Solubility of 3-methyl-2-phenyl-butanoic acid

The solubility of 3-methyl-2-phenyl-butanoic acid, also known as a branched-chain carboxylic acid, can exhibit interesting properties due to its structural features. Here are some key points to consider:

  • Polarity: This compound has a polar carboxylic acid group (-COOH) which tends to enhance its solubility in polar solvents like water.
  • Hydrophobic Character: The presence of phenyl and branched hydrocarbon sections introduces hydrophobic characteristics, potentially reducing its solubility in water.
  • Solubility in Organic Solvents: 3-methyl-2-phenyl-butanoic acid is likely to be more soluble in organic solvents such as ethanol, acetone, and diethyl ether due to its hydrophobic segments.
  • Influence of Temperature: Typically, the solubility of such compounds may increase with rising temperature, which is a general trend seen in many solutes.
  • pH Dependence: The acidity of the compound can also affect its solubility. At lower pH levels, it can exist primarily in its protonated form, influencing how it interacts with water.

In summary, while 3-methyl-2-phenyl-butanoic acid showcases attributes that may facilitate solubility, the balance between its polar and non-polar features makes its solubility behavior quite nuanced and dependent on environmental conditions.

Interesting facts

Interesting Facts about 3-Methyl-2-phenyl-butanoic Acid

3-Methyl-2-phenyl-butanoic acid is a fascinating compound that holds a special place in both organic chemistry and various industrial applications. Here are some remarkable aspects:

  • Structural Complexity: This compound is an example of a substituted carboxylic acid, featuring a combination of both a branched aliphatic chain and an aromatic group. The presence of the −COOH functional group gives it acidic properties, while the phenyl ring contributes to its unique reactivity.
  • Biological Significance: Compounds like 3-methyl-2-phenyl-butanoic acid have been explored for their potential roles in biological systems, particularly in the context of metabolic pathways and their impact on various biochemical processes.
  • Synthesis Routes: Chemists can synthesize this compound through various methods, including the use of Friedel-Crafts acylation reactions or other nucleophilic substitutions that allow for the precise introduction of the methyl and phenyl groups.
  • Flavor and Fragrance: While not widely known, some derivatives of this compound can contribute to flavor or fragrance profiles in certain industrial applications, showcasing its versatility beyond just a laboratory compound.
  • Research Opportunities: The study of 3-methyl-2-phenyl-butanoic acid can open doors to wider research in drug development, given its structural characteristics which may hint at potential pharmaceutical applications.

As a compound that bridges organic chemistry with practical applications, 3-methyl-2-phenyl-butanoic acid exemplifies the beauty and complexity of chemical substances. Its unique structure and properties make it an excellent subject for study, inviting exploration in both academic and industrial chemistry arenas.

Synonyms
3508-94-9
3-methyl-2-phenylbutanoic acid
DTXSID40928815
DTXCID001357579
622-234-8
2-ISOPROPYL-2-PHENYLACETIC ACID
alpha-Isopropylphenylacetic acid
3-Methyl-2-phenylbutyric acid
3-Methyl-2-phenyl-butyric acid
25329-47-9
3-methyl-2-phenyl-butanoic acid
MFCD00021708
BUTYRIC ACID, 3-METHYL-2-PHENYL-
(S)-3-METHYL-2-PHENYL-BUTYRIC ACID
(R)-3-Methyl-2-phenyl-butyric acid
Benzeneacetic acid, alpha-(1-methylethyl)-
NSC 22982
BRN 2045915
MFCD00167435
MFCD11505969
SCHEMBL66944
|A-Isopropylphenylacetic acid
2-phenyl-3-methylbutyric acid
2-phenyl-3-methyl-butanoic acid
Benzeneacetic acid, a-(1-methylethyl)-, sodium salt(1:1)
DAA50894
NAA49069
NSC22982
NSC-22982
AKOS009158545
SB32950
SB32951
AC-29624
AS-39413
SY025358
SY025441
SY038402
DB-021246
DS-006798
CS-0059235
Benzeneacetic acid, .alpha.-(1-methylethyl)-
EN300-93753
Z982130186