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Thioguanine

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Identification
Molecular formula
C5H5N5S
CAS number
154-42-7
IUPAC name
3-methyl-2-sulfanyl-7H-purin-6-one
State
State

At room temperature, thioguanine is in a solid state, presented as a fine powder that is stable under normal conditions.

Melting point (Celsius)
335.00
Melting point (Kelvin)
608.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
167.19g/mol
Molar mass
167.1820g/mol
Density
2.0920g/cm3
Appearence

Thioguanine is typically found as a white to off-white crystalline powder. Its fine crystalline structure allows it to be used effectively in various pharmaceutical formulations.

Comment on solubility

Solubility of 3-methyl-2-sulfanyl-7H-purin-6-one

The solubility of 3-methyl-2-sulfanyl-7H-purin-6-one, often referred to by its systematic name, varies significantly depending on the solvent used. Solubility data for this compound can be summarized as follows:

  • In Water: The solubility is generally low, making it challenging to dissolve the compound in aqueous environments.
  • In Organic Solvents: It shows better solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), which can facilitate various chemical reactions and applications.
  • Temperature Dependence: The solubility can increase with temperature; warmer conditions may assist in better dissolving.

It's important to note that the solubility of compounds like 3-methyl-2-sulfanyl-7H-purin-6-one can influence their biological activity and interaction in various environments. As stated in the literature:

"A compound's solubility is a critical factor that affects its pharmacokinetics and bioavailability."

In practical applications, understanding the solubility can directly affect formulation strategies in pharmaceuticals and biochemistry. Thus, further investigation into the solubility profile of 3-methyl-2-sulfanyl-7H-purin-6-one is essential for optimizing its use in scientific research and medicinal applications.

Interesting facts

Interesting Facts About 3-Methyl-2-sulfanyl-7H-purin-6-one

3-Methyl-2-sulfanyl-7H-purin-6-one, a fascinating compound within the purine family, is renowned for its unique structural features and biological significance. Below are some engaging facts about this compound:

  • Biological Relevance: This compound is a derivative of purines, which are essential building blocks of DNA and RNA. Its structure allows it to play a critical role in various biological processes.
  • Role in Metabolism: Compounds like 3-Methyl-2-sulfanyl-7H-purin-6-one are often involved in the metabolism of nucleotides, suggesting its potential implications in cellular energy transfer and genetic information storage.
  • Pharmaceutical Applications: Due to its sulfur-containing moiety, it is of interest for the development of drugs targeting certain metabolic disorders or diseases related to purine metabolism.
  • Natural Occurrence: Variants and derivatives similar to this compound can be found in nature, specifically in certain plant species, highlighting its potential use in herbal medicine or as a natural product in drug synthesis.
  • Chemical Versatility: The presence of both methyl and sulfanyl groups enhances the compound's reactivity and ability to form bonds with other molecules, making it attractive for synthetic organic chemistry.

In summary, 3-Methyl-2-sulfanyl-7H-purin-6-one exemplifies the intricate relationship between structure and function in biochemistry. As stated by many researchers, "The beauty of chemistry lies in its ability to unveil the connections between the smallest molecular changes and their profound biological consequences." Exploring such compounds not only enhances our understanding of cellular processes but also opens channels for innovative therapeutic strategies.