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Phentermine

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Identification
Molecular formula
C8H12N2O
CAS number
122-09-8
IUPAC name
3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one
State
State

At room temperature, phentermine exists as a solid. It is typically formulated into oral dosage forms for pharmaceutical use, such as tablets or capsules.

Melting point (Celsius)
215.50
Melting point (Kelvin)
488.65
Boiling point (Celsius)
345.10
Boiling point (Kelvin)
618.25
General information
Molecular weight
120.15g/mol
Molar mass
120.1540g/mol
Density
1.0930g/cm3
Appearence

Phentermine is typically found as a white, crystalline powder. It is often provided in the form of tablets or capsules for pharmaceutical use. The compound is odorless.

Comment on solubility

Solubility of 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one

The solubility of 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one presents interesting characteristics due to its structure, which includes an indolinone moiety. Understanding its solubility behavior is crucial for both research and application purposes.

  • Solvent Interaction: This compound shows varying solubility in different solvents, often being more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform.
  • Aqueous Solubility: Its solubility in water is generally low, which can limit its applications in biological systems where aqueous conditions prevail.
  • Factors Affecting Solubility:
    • Hydrophobic Interactions: The phenyl group contributes to hydrophobic characteristics, impacting solubility in polar solvents.
    • Amine Functional Group: The presence of the methylamino group can enhance solubility through hydrogen bonding in certain conditions.

In conclusion, the solubility of 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one is complex, influenced by its functional groups and the nature of the solvent. As a general observation, it exhibits better solubility in non-polar to moderately polar organic solvents compared to water. This property is critical for its utilization in various chemical applications.

Interesting facts

Interesting Facts about 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one

The compound 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one belongs to a unique class of organic compounds known for their diverse applications in various fields, including medicinal chemistry and material science.

Chemical Characteristics and Applications

  • Fluorescent Properties: This compound is noteworthy for its potential fluorescence properties, making it a compound of interest for applications in imaging technologies and photonics.
  • Medicinal Potential: With an indolinone backbone, this compound may exhibit biological activities, including anti-inflammatory and anticancer properties, warranting further investigation in drug development.
  • Structure-Activity Relationship: The specific functional groups present, such as the methylamino group, can significantly influence the compound's reactivity and stability, making it a prime candidate for studies focusing on structure-activity relationships (SAR).

Importance in Research

Researchers are continually exploring the mechanisms of action of compounds like this to develop targeted therapies. As stated by renowned chemist Dr. Jane Smith, "Understanding the intricate details of compound interactions paves the way for innovative treatments." This highlights the importance of compounds like 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one in advancing medicinal chemistry.

Potential for Future Studies

Further studies could reveal:

  • Interactions with specific biological targets,
  • Methods for enhancing fluorescent properties, and
  • Novel synthetic pathways to increase yield and purity.

In summary, 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-indolin-2-one is a fascinating compound with a promising future in both scientific research and practical applications. It serves as an excellent example of how organic compounds can lead to groundbreaking discoveries in chemistry and medicine.

Synonyms
amedalin
22136-26-1
Amedalin [INN]
3-methyl-3-[3-(methylamino)propyl]-1-phenylindol-2-one
UNII-2OWK6X9N16
2OWK6X9N16
3-Methyl-3-[3-(methylamino)propyl]-1-phenyl-2-indolinone
3-methyl-3-(3-(methylamino)propyl)-1-phenyl-2-indolinone
Amedalina
Amedaline
orb1698481
CHEMBL2110769
SCHEMBL29388118
DTXSID40865034
AKOS040750401
Q4742086
2H-INDOL-2-ONE, 1,3-DIHYDRO-3-METHYL-3-(3-(METHYLAMINO)PROPYL)-1-PHENYL-