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3-Methyl-3-phenylazetidine

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Identification
Molecular formula
C10H13N
CAS number
4934-47-4
IUPAC name
3-methyl-3-phenyl-azetidine
State
State

At room temperature, 3-methyl-3-phenylazetidine can exist as a low-melting solid or liquid, depending on the ambient temperature. It is typically in a liquid state slightly above its melting point.

Melting point (Celsius)
37.00
Melting point (Kelvin)
310.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
147.22g/mol
Molar mass
147.2200g/mol
Density
1.0150g/cm3
Appearence

3-Methyl-3-phenylazetidine typically appears as a colorless liquid or solid, although specific appearance can vary depending on the form and purity. It may exhibit a slight yellowish tint if impurities are present.

Comment on solubility

Solubility of 3-methyl-3-phenyl-azetidine

When examining the solubility characteristics of 3-methyl-3-phenyl-azetidine, it's essential to consider several factors that influence its behavior in various solvents. This compound, given its unique structure, may demonstrate the following solubility preferences:

  • Polar Solvents: 3-methyl-3-phenyl-azetidine may show limited solubility in polar solvents due to the non-polar nature of its phenyl group, which resists interactions with polar molecules.
  • Non-Polar Solvents: This compound is likely to be more soluble in non-polar solvents such as hexane or benzene. The hydrophobic character contributed by the phenyl ring enhances its affinity for non-polar environments.
  • Temperature Influence: Solubility can vary significantly with temperature. Generally, increasing the temperature may enhance solubility, particularly in non-polar solvents, as the kinetic energy of the molecules increases.

In summary, while 3-methyl-3-phenyl-azetidine is expected to be sparingly soluble in polar solvents, it is likely to dissolve more readily in non-polar solvents. Understanding these solubility trends is crucial for applications in synthesis, formulation, and various chemical processes.

Interesting facts

Interesting Facts about 3-Methyl-3-phenyl-azetidine

The compound 3-Methyl-3-phenyl-azetidine is an intriguing member of the azetidine family, which are four-membered heterocyclic compounds containing nitrogen. Here are some fascinating aspects of this compound:

  • Structural Characteristics: 3-Methyl-3-phenyl-azetidine features a nitrogen atom within its ring structure, lending it unique chemical reactivity. The presence of both a methyl group and a phenyl group contributes to its versatility in synthesis.
  • Synthetic Applications: This compound serves as an important intermediate in organic synthesis. Its structure allows it to be a precursor for various other compounds, making it valuable for pharmaceutical and agrochemical development.
  • Biological Activity: Compounds similar to azetidine derivatives have shown potential in medicinal chemistry. Research suggests that azetidines may exhibit antimicrobial and anti-inflammatory properties, paving the way for further investigations into their biological applications.
  • Research Interest: Due to its unique ring closure, 3-methyl-3-phenyl-azetidine garners attention in studies focusing on ring strain and stability, helping chemists understand how structural modifications affect reactivity.
  • Literature Insights: The compound has been mentioned in various academic papers, illustrating its relevance in synthetic methodologies and material science. Scientists continue to explore the implications of azetidine derivatives in drug design.

As you can see, 3-methyl-3-phenyl-azetidine is not just a simple compound; it holds significant promise in the realms of chemistry and medicine, revealing an exciting landscape for future research and practical applications!

Synonyms
3-Methyl-3-phenylazetidine
5961-33-1
AZETIDINE, 3-METHYL-3-PHENYL-
BRN 0116363
DTXSID60208287
DTXCID80130778
5-20-06-00368 (beilstein handbook reference)
yollumurpueojw-uhfffaoysa-n
L 1834
SCHEMBL16488091
CHEBI:90060
3-METHYL-3-PHENYL AZETIDINE
AKOS006280360
SB50870
DB-411201
CS-0279395
EN300-202483
Q27162284