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Cefazolin

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Identification
Molecular formula
C14H14N8O4S
CAS number
25953-19-9
IUPAC name
3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, cefazolin is a solid which is often used in a lyophilized or powder form for reconstitution as an injectable drug. It tends to be stable when kept in its appropriate conditions.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
454.50g/mol
Molar mass
454.5030g/mol
Density
1.6910g/cm3
Appearence

Cefazolin typically appears as a white to off-white crystalline powder. It is almost odorless and is known for its purity and stability in its pure form. This compound is frequently used in a lyophilized form for injections.

Comment on solubility

Solubility of 3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of the compound 3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4<lambda>6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C14H14N8O4S) is influenced by several factors, including its structural complexity and the presence of functional groups. Understanding solubility can provide insights into the compound’s behavior in various environments. Here are some critical points to consider:

  • Polarity: Due to the presence of polar functional groups such as carboxylic acid and triazole within the structure, the compound is expected to demonstrate a degree of solubility in polar solvents like water.
  • Hydrogen bonding: The ability of the compound to form hydrogen bonds may enhance its solubility in aqueous solutions. The –COOH group greatly contributes to this property.
  • Drug solubility: If this compound is considered for pharmaceutical applications, its solubility profile will significantly affect its bioavailability.
  • Temperature dependence: Solubility can be temperature-dependent, so changes in temperature may alter the solubility characteristics.

In summary, while it is crucial to explore laboratory data to confirm solubility, the inherent properties of C14H14N8O4S suggest a potential for solubility in polar environments, driven by its structural features and functional groups.

Interesting facts

3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This intriguing compound belongs to a class of complex organic molecules that exemplify the stunning diversity of chemical structures found in nature. Its unique framework includes a triazole moiety, a five-membered ring known for its applications in medicinal chemistry. Here are some fascinating facts about this compound:

  • Potential Pharmacological Applications: The presence of both the triazole and bicyclic structure hints at possible biological activity, making it an interesting candidate for drug discovery.
  • Synthetic Challenges: The multi-functional groups within this molecule can present synthetic challenges, often requiring advanced techniques in organic synthesis for its preparation.
  • Architectural Complexity: The bicyclic system and the incorporation of sulfur and nitrogen within its structure contribute to a rich tapestry of chemical interactions, highlighting the intricate designs that can be achieved through molecular synthesis.
  • Research Interest: Compounds with this type of structure are frequently studied for their potential anti-cancer, anti-inflammatory, or antimicrobial properties.

As a chemistry student or a scientist, one can marvel at how such sophisticated structures can lead to advancements in therapeutic agents. The exploration of compounds like this one is not just about understanding their properties, but also about discovering novel applications that can impact health and industry.

As the field of medicinal chemistry continues to evolve, the study of complex compounds such as this one remains pivotal. The integration of various functional groups presents opportunities for innovative drug design, potentially leading to the next breakthrough in medicine.

Synonyms
Tazobactam;Tazobactan acid
81546-15-8
MFCD00867002
1246733-29-8
Tazobactam (Free acid)
SCHEMBL13437219
DTXSID80861116
LPQZKKCYTLCDGQ-UHFFFAOYSA-N
LS-13789
SY104963
3-((1H-1,2,3-Triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
3-((1H-1,2,3-Triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid4,4-dioxide
3-Methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda~6~-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid