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3-Methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one

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Identification
Molecular formula
C19H13N3O2
CAS number
798-67-8
IUPAC name
3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one
State
State

At room temperature, 3-Methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one is typically in a solid state, characterized by its crystalline structure.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
473.50
Boiling point (Kelvin)
746.65
General information
Molecular weight
290.33g/mol
Molar mass
290.3070g/mol
Density
1.2892g/cm3
Appearence

3-Methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one typically appears as a solid crystalline material, often with a faint color ranging from off-white to pale yellow, depending on specific sample purity and conditions.

Comment on solubility

Solubility of 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one

The solubility of 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one can be influenced by various factors, including its molecular structure and the presence of functional groups. Generally, the solubility of organic compounds can be assessed in different solvents:

  • Polar solvents: Due to the presence of polar functional groups, this compound may exhibit limited solubility in highly polar solvents such as water.
  • Non-polar solvents: It is likely to have better solubility in non-polar organic solvents like hexane or chloroform, due to its aromatic character and hydrophobic regions.
  • Amphipathic solubility: If the compound possesses characteristics of both polar and non-polar regions, it may display amphipathic behavior, affecting its solubility in mixed solvent systems.

The level of solubility can also depend on temperature, with solubility typically increasing as temperature rises. Furthermore, the presence of other solutes and alterations in ionic strength can influence solubility, making empirical measurements necessary for precise data.

In summary, while the solubility of 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one in polar solvents may be low, it is expected to dissolve better in non-polar environments. Understanding these solubility characteristics is key for applications in synthesis and formulation.

Interesting facts

Interesting Facts about 3-Methyl-4,6-Diphenyl-Isoxazolo[3,4-d]Pyridazin-7-One

The compound 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one is a fascinating member of the isoxazole class, an important group in organic chemistry known for their diverse applications. Here are some intriguing aspects of this unique compound:

  • Structural Diversity: This compound showcases a complex structure that combines both isoxazole and pyridazine rings, resulting in a rich chemical landscape that is highly valuable for the development of various therapeutic agents.
  • Biological Activity: Many isoxazole derivatives have been noted for their pharmaceutical potential. Research indicates that compounds similar to 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one may exhibit interesting biological activities, including anti-inflammatory and anti-cancer properties.
  • Synthetic Routes: The synthesis of this compound typically involves multi-step organic reactions that might include cyclization reactions, which can be a challenging yet rewarding aspect of synthetic organic chemistry.
  • Research Interest: Due to its unique structural features, there is ongoing research to explore the full spectrum of activities and potential applications of this compound in medicinal chemistry.

As noted by one researcher, "The exploration of compounds like 3-methyl-4,6-diphenyl-isoxazolo[3,4-d]pyridazin-7-one opens the door to understanding new pathways in drug development and materials science."
This compound serves as a reminder of the rich potential that lies within organic molecules, and continues to inspire both chemists and students alike in their quest for innovation.

Synonyms
25506-01-8
ISOXAZOLO(3,4-d)PYRIDAZIN-7(6H)-ONE, 4,6-DIPHENYL-3-METHYL-
BRN 1146202
4,6-Diphenyl-3-methylisoxazolo(3,4-d)pyridazin-7(6H)-one
3-Metil-4,6-difenilisossazolo(3,4-d)piridazin-7-one [Italian]
DTXSID40180198
3-Metil-4,6-difenilisossazolo(3,4-d)piridazin-7-one
RefChem:350276
DTXCID50102689
3-methyl-4,6-diphenyl-[1,2]oxazolo[3,4-d]pyridazin-7-one
HMS546H16
Maybridge1_001754
Oprea1_766383
MLS000851059
CHEMBL1411655
HMS2796F11
3-Methyl-4,6-di(phenyl)-[1,2]oxazolo[3,4-d]pyridazin-7-one
BTB 09043
CCG-42372
NCGC00246657-01
SMR000457302
SR-01000632377-1
3-methyl-4,6-diphenyl-6,7-dihydroisoxazolo[3,4-d]pyridazin-7-one