Skip to main content

3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one

ADVERTISEMENT
Identification
Molecular formula
C10H7N4O3S2
CAS number
Unavailable
IUPAC name
3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one
State
State

At room temperature, this compound is in a solid state. The azo and thiazolidinone groups influence its stability and solid-state properties, maintaining its solidity till it reaches its melting point.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
336.41g/mol
Molar mass
336.4100g/mol
Density
1.5600g/cm3
Appearence

The compound is typically a solid with a yellow to orange coloration. It is crystalline in nature, and the presence of azo and nitro groups usually contributes to its vibrant color. The crystalline structure facilitates the compound's solid form at room temperature.

Comment on solubility

Solubility of 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one

The solubility of the compound 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one can be quite fascinating due to its unique structure. Here are some key aspects to consider:

  • Solvent Dependence: The solubility of this compound may vary significantly depending on the solvent used.
    It is typically more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) than in water.
  • Polar vs. Non-Polar: As a compound containing both polar and non-polar functional groups, its solubility is subject to the "like dissolves like" principle, suggesting that it will favorably dissolve in solvents that match these characteristics.
  • Temperature Effects: Increasing the temperature often enhances the solubility of organic compounds, which might apply here as well. Thus, warming the solution could lead to better dissolution rates.
  • pH Sensitivity: Due to the presence of nitrophenyl and thiazolidin moieties, the solubility may be affected by the pH of the solution. Acidic conditions might alter the protonation state and therefore influence its solubility.

In conclusion, understanding the solubility of 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one is essential for applications in synthesis and formulation, as solubility is a critical factor that governs the behavior of compounds in various environments.

Interesting facts

3-Methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one: An In-depth Exploration

The compound 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one is a fascinating member of the thiazolidinone family, known for its diverse applications in various fields of chemistry. Here are some intriguing aspects worth noting:

  • Diverse Applications: This compound has garnered interest in medicinal chemistry, as derivatives of thiazolidinones often exhibit noteworthy biological activities, including anti-inflammatory and antimicrobial properties.
  • Structural Significance: The presence of both an azo group and a nitrophenyl moiety helps to enhance the stability and reactivity of the compound, making it a suitable candidate for further modifications.
  • Important Functional Groups: The thioxo and thiazolidinone functionalities contribute to the compound's unique chemical behavior, allowing it to participate in a wide range of chemical reactions.
  • Potential Research Opportunities: The intriguing structure of this compound opens doors for extensive research, especially in the development of novel pharmaceuticals. As noted by researchers, "Understanding the reactivity of thiazolidinone derivatives is crucial for future drug design."
  • Colorimetric Properties: Compounds that contain azo groups are often known for their vivid coloration, making them significant not just in pharmaceuticals but also in dyes and indicators.

In conclusion, 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one stands at the intersection of synthetic organic chemistry and medicinal applications. Its unique structural features are a platform for innovative research, showcasing the endless possibilities within chemical compounds.

Synonyms
NITRODAN
Nidanthel
Everfree
962-02-7
CTR 6110
NSC-44646
NSC-67817
2STG09LA8F
3-Methyl-5-(4-nitrophenylazo)rhodanine
MLS002608645
CTR-6110
Nitrodan (USAN)
NSC44646
NSC67817
3-methyl-5-[(4-nitrophenyl)diazenyl]-2-sulfanylidene-1,3-thiazolidin-4-one
3-Methyl-5-(4'-nitrophenylazo)rhodanine
3-Methyl-5-((p-nitrophenyl)azo)rhodanine
3-Methyl-5-[(p-nitrophenyl)azo]rhodanine
NITRODAN [USAN]
Rhodanine, 3-methyl-5-[(p-nitrophenyl)azo]-
Nitrodanum
4-Thiazolidinone, 3-methyl-5-[(4-nitrophenyl)azo]-2-thioxo-
Nitrodano
Rhodanine, 3-methyl-5-(p-nitrophenylazo)-
Nitrodan [USAN:INN]
RHODANINE, 3-METHYL-5-((P-NITROPHENYL)AZO)-
UNII-2STG09LA8F
4-Thiazolidinone, 3-methyl-5-((4-nitrophenyl)azo)-2-thioxo-
NSC 44646
NSC 67817
3-Methyl-5-((4-nitrophenyl)azo)rhodanin
NITRODAN [INN]
NITRODAN [MI]
NCIOpen2_003502
SCHEMBL634769
SCHEMBL6738937
CHEMBL1707960
CHEMBL2106768
DTXSID70862490
HMS3082E05
NS00121912
D05185
Rhodanine, 3-methyl-5-[ (4-nitrophenyl)azo]-
Q27255553
3-methyl-5-(p-nitrophenylazo )-2-thioxothiazolidin-4-on
4-Thiazolidinone, 3-methyl-5-[ (4-nitrophenyl)azo]-2-thioxo-
3-METHYL-5-(P-NITROPHENYLAZO)-2-THIOXOTHIAZOLIDIN-4-ONE
3-methyl-5-[(E)-(4-nitrophenyl)azo]-2-thioxo-thiazolidin-4-one
4-Thiazolidinone, 3-methyl-5-[(E)-2-(4-nitrophenyl)diazenyl]-2-thioxo-
2,3-DIHYDRO-3-METHYL-5-((4-NITROPHENYL)AZO)-2-THIOXO-4(5H)-THIAZOLONE
4-THIAZOLIDINONE, 3-METHYL-5-(2-(4-NITROPHENYL)DIAZENYL)-2-THIOXO-