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Harmane

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Identification
Molecular formula
C13H14N2
CAS number
486-84-0
IUPAC name
3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
State
State

At room temperature, Harmane is a solid.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
394.00
Boiling point (Kelvin)
667.15
General information
Molecular weight
196.27g/mol
Molar mass
196.2730g/mol
Density
1.2048g/cm3
Appearence

Harmane is a pale yellow to yellow crystalline solid.

Comment on solubility

Solubility of 3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

The solubility of the compound 3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole can be quite complex due to its intricate molecular structure and functional groups. Understanding its solubility characteristics is essential for various applications, including pharmacology and materials science. Here are some critical points regarding its solubility:

  • Polarity: The presence of nitrogen atoms in the pyridine group increases the polarity of the compound, potentially enhancing its solubility in polar solvents.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic (water-attracting) and hydrophobic (water-repelling) segments in the molecule can affect solubility.
  • Solvent Interaction: This compound may dissolve well in organic solvents like ethanol or dimethyl sulfoxide (DMSO) rather than in water.
  • Temperature Influence: As with many compounds, increasing temperature may increase solubility in certain solvents.
  • Crystallization: Solubility can affect crystallization processes, which are critical in drug formulation, where a specific solubility profile is desired.

In summary, the solubility of this compound is influenced by multiple factors, including its polarity, solvent interactions, and molecular structure. Understanding these characteristics can provide insights into its behavior in various environments and enhance its practical applications.

Interesting facts

Interesting Facts about 3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

The compound known as 3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a fascinating member of the indole family, which are significant in the realm of pharmaceuticals and other chemical applications. Here are some noteworthy facts:

  • Structural Complexity: This compound features a multi-ring structure that incorporates both pyridine and indole functionalities, showcasing the diversity and intricacy often found in organic compounds.
  • Biological Activity: Compounds like this one may exhibit various biological activities, including potential roles in neuropharmacology. Indoles and their derivatives have been noted for their effects on neurotransmitter systems.
  • Synthetic Opportunities: The unique arrangement of methyl and pyridine groups opens avenues for synthetic chemists to explore and develop novel methodologies for creating similar compounds.
  • Therapeutic Potential: Research indicates that such structures can mimic biologically relevant molecules, making them candidates for drug development in areas such as antidepressants or other central nervous system therapies.
  • Interdisciplinary Impact: The interplay of chemistry, biology, and pharmacology in studying compounds like this highlights the importance of interdisciplinary approaches in scientific research.

In conclusion, 3-methyl-9-[2-(6-methyl-3-pyridyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole exemplifies the intricate designs of organic molecules and their potential implications in health and medicine. As noted in the field, "The beauty of chemistry lies in its endless possibilities for creation and discovery."

Synonyms
2,3,4,5-Tetrahydro-2-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole
20674-91-3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
BRN 0621868
3-methyl-9-[2-(6-methylpyridin-3-yl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
DTXSID00942870
CBHKORLHJIYAKT-UHFFFAOYSA-N
1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2-methyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-
2-METHYL-5-(2-(6-METHYL-3-PYRIDYL)ETHYL)-1,2,3,4-TETRAHYDRO-GAMMA-CARBOLINE
3-Methyl-9-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole #
9-(2-(2-Methyl-5-pyridyl)ethyl)-3-methyl-1,2,3,4-tetrahydro-.gamma.-carboline