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3-Methylglutarimide

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Identification
Molecular formula
C6H9NO2
CAS number
21655-86-3
IUPAC name
3-methylpiperidine-2,6-dione
State
State
At room temperature, 3-Methylglutarimide is a solid with a crystalline structure.
Melting point (Celsius)
81.00
Melting point (Kelvin)
354.15
Boiling point (Celsius)
239.00
Boiling point (Kelvin)
512.15
General information
Molecular weight
127.15g/mol
Molar mass
127.1570g/mol
Density
1.1872g/cm3
Appearence
3-Methylglutarimide is typically a white crystalline solid. Its structure consists of a six-membered saturated ring with a cyclic amide, imparting it with rigid geometry and solid form. The compound is known for its stability and its ability to form colorless crystals.
Comment on solubility

Solubility of 3-methylpiperidine-2,6-dione

3-methylpiperidine-2,6-dione, a cyclic amide compound, demonstrates unique solubility characteristics that are influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polar Nature: The ability of 3-methylpiperidine-2,6-dione to interact with polar solvents helps enhance its solubility in water and other protic solvents.
  • Hydrophilicity: Due to the presence of carbonyl groups, this compound exhibits hydrophilic properties, contributing to its dissolution in various aqueous environments.
  • Solvent Specificity: While it is soluble in polar solvents, its solubility in non-polar solvents is typically limited. This means that:
    • It may dissolve well in solvents such as methanol, ethanol, and acetone.
    • It is likely to have low solubility in hydrocarbons, such as hexane or cyclohexane.
  • Temperature Influence: The solubility can vary with temperature changes, often improving in higher temperatures due to increased molecular motion.

In summary, the solubility of 3-methylpiperidine-2,6-dione is significant in polar solvents while exhibiting limited capability in non-polar environments, making its solubility profile particularly interesting for various chemical applications.

Interesting facts

Exploring 3-Methylpiperidine-2,6-dione

3-Methylpiperidine-2,6-dione is an intriguing compound in the realm of organic chemistry, mainly recognized for its multifaceted roles in synthetic applications. Here are some captivating insights into this compound:

  • Structural Characteristics: This compound features a six-membered saturated nitrogen-containing ring, which is a characteristic of piperidine derivatives. The presence of two carbonyl groups at the 2 and 6 positions imparts unique reactivity profiles.
  • Importance in Synthesis: Often used as a building block in the synthesis of more complex molecules, 3-methylpiperidine-2,6-dione serves as a precursor for various pharmaceuticals and agrochemicals. Its ability to undergo further transformations makes it valuable in drug discovery and materials science.
  • Biological Activity: The derivatives of this compound exhibit potential biological activities, ranging from antimicrobial to anti-inflammatory properties. Researchers are consistently exploring its derivatives for therapeutic applications.
  • Functional Group Diversity: The molecule showcases significant functional group diversity, contributing to its versatility in reactions such as nucleophilic addition and cyclization, enhancing its utility in organic synthesis.

As a student of chemistry, one might find 3-methylpiperidine-2,6-dione not just a subject of study, but a gateway to understanding the broader implications of chemical synthesis and medicinal chemistry. The compound is a testament to how simple structures can lead to robust chemical functionalities.

In conclusion, the study of 3-methylpiperidine-2,6-dione1 opens up avenues for innovative research and application, showcasing the exciting nature of organic compounds in chemistry.

Synonyms
29553-51-3
RefChem:1068185
3-Methyl-2,6-piperidinedione
3-METHYLPIPERIDINE-2,6-DIONE
2,6-Piperidinedione, 3-methyl-
MFCD13178824
methylglutarimide
SCHEMBL493044
3-methyl-piperidine-2,6-dione
SCHEMBL28650545
DTXSID30952048
DKCRDQKHMMPWPG-UHFFFAOYSA-N
EBA55351
AKOS013476917
SB41310
DS-16018
SY111878
DB-094336
CS-0061420
EN300-220036
W17200
F231754
6-Hydroxy-3-methyl-4,5-dihydropyridin-2(3H)-one