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3-picoline

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Identification
Molecular formula
C6H7N
CAS number
108-99-6
IUPAC name
3-methylpyridine
State
State

At room temperature, 3-methylpyridine is a liquid. It is commonly used as a solvent and in the manufacture of various derivatives.

Melting point (Celsius)
-16.00
Melting point (Kelvin)
257.15
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.15
General information
Molecular weight
93.13g/mol
Molar mass
93.1310g/mol
Density
0.9574g/cm3
Appearence

3-Methylpyridine, also known as 3-picoline, is a colorless liquid with a slightly unpleasant odor. It is typically found in its liquid state and is miscible with water, alcohol, and ether.

Comment on solubility

Solubility of 3-methylpyridine

3-methylpyridine, also known as collidine, is a member of the pyridine family that exhibits notable solubility characteristics. This compound is known for its ability to dissolve in various solvents, which makes it versatile in chemical applications.

Key Solubility Insights:

  • Water Solubility: 3-methylpyridine has a moderate solubility in water, typically due to its polar nature, but it is significantly less soluble than its more hydrophilic counterparts.
  • Organic Solvents: It is highly soluble in a wide range of organic solvents, including ethanol, ether, and chloroform, making it a useful solvent itself in organic chemistry.
  • Temperature Influence: The solubility can be influenced by temperature—increased temperature often enhances solubility, especially in organic solvents.

In practice, when working with 3-methylpyridine, it is crucial to consider the desired solvent environment, as its unique solubility properties can significantly impact reactions and formulations. As with many organic compounds, understanding solubility not only aids in practical applications but also helps in predicting behavior in various chemical systems.

Interesting facts

Interesting Facts about 3-Methylpyridine

3-Methylpyridine, also known as methyl-3-pyridine, is a fascinating compound in the field of organic chemistry, belonging to the class of heterocyclic compounds. Here are some intriguing aspects to consider about this molecule:

  • Structure and Isomerism: Being a derivative of pyridine, 3-methylpyridine is characterized by a methyl group attached to the third carbon of the pyridine ring. This positioning leads to its classification as a meta isomer, distinct from its ortho and para counterparts, a feature that dramatically influences its chemical behavior.
  • Applications: This compound is widely used in various industrial applications. It's particularly valued in the synthesis of agrochemicals and pharmaceuticals. It's also a crucial solvent and intermediate in chemical manufacturing, highlighting its versatility in organic synthesis.
  • Flavor and Fragrance: Interestingly, 3-methylpyridine contributes to the flavor profile of certain foods. Its aromatic properties are utilized in the food industry, particularly in enhancers, where it adds unique sensory characteristics.
  • Biological Activity: Research has shown that certain derivatives of 3-methylpyridine possess biological activity. The compound itself is also studied for its role in various metabolic processes and potential therapeutic applications.
  • Environmental Presence: 3-Methylpyridine finds its way into the environment through various routes, including agricultural runoff and industrial discharge. Studying its degradation pathways and environmental impact is crucial for ecological preservation.
  • Research Potential: Due to its unique properties, 3-methylpyridine remains a subject of ongoing research. Scientists explore its potential in synthesizing novel materials, including conductive polymers and organic electronics.

In summary, 3-methylpyridine showcases the intricate relationship between structure and function in organic chemistry. As chemists continue to investigate its applications and properties, this compound serves as a reminder of the complexity found within seemingly simple molecules.

Synonyms
3-METHYLPYRIDINE
3-Picoline
108-99-6
beta-Picoline
Pyridine, 3-methyl-
m-Picoline
m-Methylpyridine
B-Picoline
beta-Methylpyridine
.beta.-Picoline
NSC 18251
3-Mepy
.beta.-Methylpyridine
CCRIS 1722
HSDB 4254
EINECS 203-636-9
UNII-B083J4KF7F
B083J4KF7F
DTXSID9021897
CHEBI:39922
AI3-24110
NSC-18251
METHYLPYRIDINE, 3-
DTXCID201897
EC 203-636-9
3-Methyl pyridine
meta-Methylpyridine
CAS-108-99-6
MFCD00006402
3-methypyridine
5-methylpyridine
3-methyl pyridin
3-methyl-pyridine
pyridine, 3-methyl
3-Methylpyridine, 99%
beta-PICOLINE (IARC)
NCIOpen2_004641
MLS001065607
CHEMBL15722
.BETA.-PICOLINE [MI]
3-Picoline, analytical standard
.BETA.-PICOLINE [IARC]
3-METHYLPYRIDINE [HSDB]
3-Methylpyridine, >=99.5%
HMS3039L05
BCP22897
BCP26368
NSC18251
Tox21_201966
Tox21_303001
STL282747
AKOS000119862
DB01996
FM02830
NCGC00091447-01
NCGC00091447-02
NCGC00256559-01
NCGC00259515-01
PICOLINE (FLAMMABLE LIQUID LABEL)
PD008234
SMR000568465
DB-016018
m-Picoline [UN2313] [Flammable liquid]
NS00002252
P0416
EN300-19742
Q2697560
F0001-0187
Z104475010
InChI=1/C6H7N/c1-6-3-2-4-7-5-6/h2-5H,1H
203-636-9
5HS