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3-(Morpholino)chromone

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Identification
Molecular formula
C13H13NO4
IUPAC name
3-(morpholine-4-carbonyl)chromen-2-one
State
State

The compound is typically in a solid state at room temperature. It is stable under standard conditions but should be stored in a cool, dry place.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
245.26g/mol
Molar mass
245.2630g/mol
Density
1.3445g/cm3
Appearence

3-(Morpholino)chromone appears as a crystalline powder. It has a characteristic appearance that can vary from off-white to light brown, depending on purity and specific conditions of synthesis.

Comment on solubility

Solubility of 3-(morpholine-4-carbonyl)chromen-2-one

The solubility characteristics of 3-(morpholine-4-carbonyl)chromen-2-one can be intriguing due to its unique molecular structure. Understanding the solubility behavior of this compound is essential for applications in various fields, such as pharmaceuticals and organic chemistry.

  • Polar vs. Non-Polar: This compound exhibits both polar and non-polar characteristics due to the presence of the morpholine group and the chromenone structure. Generally, compounds containing polar functional groups tend to have better solubility in polar solvents.
  • Intermolecular Interactions: The morpholine ring may contribute to increased solubility in water through hydrogen bonding with the solvent, whereas the chromenone moiety can influence solubility in organic solvents.
  • Specific Solvent Compatibility: It is likely that 3-(morpholine-4-carbonyl)chromen-2-one will be soluble in:
    • Polar solvents such as dimethyl sulfoxide (DMSO)
    • Moderately polar solvents like ethanol or methanol
    • Potentially sparingly soluble in non-polar solvents

In summary, the solubility of 3-(morpholine-4-carbonyl)chromen-2-one can be affected by the solvent's polarity, the temperature, and the presence of other solubilizing agents. As a general principle: "Like dissolves like." Thus, predicting solubility requires a careful evaluation of molecular interactions. Understanding these factors is crucial for manipulating the use of this compound in various chemical applications.

Interesting facts

Interesting Facts about 3-(Morpholine-4-carbonyl)chromen-2-one

3-(Morpholine-4-carbonyl)chromen-2-one, a fascinating compound, belongs to a class of chemicals known for their complex structures and varied applications. Here are some highlights that make this compound particularly interesting:

  • Structural Significance: The incorporation of the morpholine ring adds a unique dimensional aspect to the compound, which can influence its reactivity and interactions in biological contexts.
  • Biological Applications: Compounds containing the chromen backbone are widely studied for their potential pharmacological properties. They have shown promise in various therapeutic areas, including anti-inflammatory, anti-cancer, and anti-viral activities.
  • Synthetic Versatility: The synthesis of 3-(Morpholine-4-carbonyl)chromen-2-one can serve as an important example for chemists exploring new methodologies in organic synthesis, particularly in the formation of heterocycles.
  • Fluorescent Properties: Some derivatives of chromen-2-one exhibit fluorescence, making them useful in imaging and detection applications in the biological sciences.

As chemists delve deeper into the applications and characteristics of this compound, it highlights the intricate dance between structure and activity in medicinal chemistry. This compound exemplifies the importance of finding novel compounds that can lead to improved therapeutic strategies.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Studying compounds like 3-(Morpholine-4-carbonyl)chromen-2-one is essential for sparking innovative ideas in the search for new drugs.

Synonyms
3-(Morpholinocarbonyl)coumarin
18144-52-0
3-(morpholine-4-carbonyl)chromen-2-one
COUMARIN, 3-(MORPHOLINOCARBONYL)-
3-(morpholine-4-carbonyl)-2H-chromen-2-one
CHEMBL451208
2H-1-Benzopyran-2-one, 3-(4-morpholinylcarbonyl)-
BRN 0277785
3-(Morpholine-4-carbonyl)-chromen-2-one
Enamine_001646
3-(morpholin-4-ylcarbonyl)-2H-chromen-2-one
Oprea1_101160
Oprea1_845574
CBDivE_002099
4-27-00-00529 (Beilstein Handbook Reference)
cid_28914
MLS000526098
Coumarine, 3-morpholinocarbonyl-
DTXSID00171148
SLSKQRHMOPTNAU-UHFFFAOYSA-N
HMS1398K18
HMS2757D07
3-(Morpholino-4-carbonyl)coumarin
BDBM50244453
STK337560
3-morpholinocarbonyl-2h-chromen-2-one
AKOS000522243
NCGC00245499-01
NCGC00245499-02
3-(morpholin-4-ylcarbonyl)chromen-2-one
SMR000116572
ST4015341
3-(4-Morpholinylcarbonyl)-2H-chromen-2-one
3-(4-Morpholinylcarbonyl)-2H-chromen-2-one #
AB00125966-09
SR-01000403870
SR-01000403870-1
Z31721650
F0777-0625
Morpholine, 4-[(2-oxo-2H-1-benzopyran-3-yl)carbonyl]-