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Iopromide

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Identification
Molecular formula
C18H24I3N3O8
CAS number
73334-07-3
IUPAC name
3-(N-acetyl-3-amino-2,4,6-triiodo-anilino)-2-methyl-propanoic acid
State
State

At room temperature, Iopromide is generally a solid.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
791.12g/mol
Molar mass
791.1200g/mol
Density
2.0000g/cm3
Appearence

Iopromide appears as an off-white to pale yellow crystalline powder.

Comment on solubility

Solubility of 3-(N-acetyl-3-amino-2,4,6-triiodo-anilino)-2-methyl-propanoic acid

The solubility of 3-(N-acetyl-3-amino-2,4,6-triiodo-anilino)-2-methyl-propanoic acid is influenced by both its molecular structure and functional groups. This compound features a combination of bulky iodine atoms and an acetamido functional group, which impacts its interaction with solvents. Here are key points regarding its solubility:

  • Polar Characteristics: Due to the presence of the carboxylic acid group, the compound can exhibit polar characteristics, making it potentially more soluble in polar solvents like water.
  • Non-Polar Influences: The triiodophenyl group may introduce non-polar characteristics, which can reduce its overall solubility in strictly polar environments.
  • Hydrogen Bonding: The ability to participate in hydrogen bonding through its amine and carboxylic acid groups may enhance solubility in water and other polar solvents.
  • Concentration Effect: At higher concentrations, the solubility may vary significantly due to the formation of aggregates or complexes with solvents.

As a result, the solubility of this compound may not be straightforward and can depend on factors such as temperature, pH, and the presence of other solutes. In summary, while predictions about solubility can be made based on functional groups, empirical testing is often necessary to determine the exact solubility profile of such complex compounds.

Interesting facts

Interesting Facts about 3-(N-acetyl-3-amino-2,4,6-triiodo-anilino)-2-methyl-propanoic acid

This fascinating compound belongs to a class of chemical substances that are notable for their potential utility in various fields, particularly in medicinal chemistry and pharmaceuticals. Here are some intriguing aspects of this compound:

  • Complex Structure: The compound features a complex molecular structure which includes multiple functional groups, notably the triiodo-anilino moiety that enhances its biological activity.
  • Medicinal Applications: Compounds of this nature are often synthesized for their potential use in therapeutic applications, including as contrast agents in medical imaging, owing to their iodine content.
  • Biodistribution: The iodine atoms in its structure play a crucial role in defining its biodistribution in the body, which can help in visualizing biological processes during diagnostic procedures.
  • Research Significance: The presence of both amino and acetyl functionalities suggests that this compound could be a subject of intense research interest, particularly for modifying amino acids or peptides.
  • Environmental Impact: Like many iodine-containing compounds, it warrants study regarding its environmental fate and potential bioaccumulation in ecological systems.
  • Thermodynamic Properties: While the exact thermodynamic properties are not specified, the compound's structure likely gives rise to interesting interactions that can impact its physical properties and reactivity.

In summary, 3-(N-acetyl-3-amino-2,4,6-triiodo-anilino)-2-methyl-propanoic acid is not just a chemical compound but a gateway to exploring complex interactions within biological systems, making it an impressive subject for both researchers and students delving into chemical sciences.

Synonyms
IOCETAMIC ACID
Cholebrine
16034-77-8
Cholimil
Colebrina
MP-620
DRC 1201
MP 620
FA675Q0E3E
DTXSID2023149
N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-beta-alanine
3-(N-(3-Amino-2,4,6-triiodophenyl)acetamido)-2-methylpropanoic acid
Propanoic acid, 3-(acetyl(3-amino-2,4,6-triiodophenyl)amino)-2-methyl-
DTXCID303149
N-Acetyl-N-(3-amino-2,4,6-triiodophenl)-2-methyl-beta-alanine
beta-Alanine, N-acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-
N-Acetyl-N-(2,4,6-triiodo-3-aminophenyl)-beta-aminoisobutyric acid
N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-beta-aminoisobutyric acid
3-(Acetyl-(3-amino-2,4,6-triiodophenyl)amino)-2-methylpropanoic acid
Propionic acid, 3-(acetyl-(3-amino-2,4,6-triiodophenyl)amino)-2-methyl-
3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
240-173-1
Acido iocetamico
Acide iocetamique
3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic acid
Iocetamic acid (USAN)
Acidum jocetamicum
Cholimil; DRC 1201; Iocetamic acid; MP 620
IOCETAMIC ACID [USAN]
3-[acetyl(3-amino-2,4,6-triiodophenyl)amino]-2-methylpropanoic acid
Acidum iocetamicum
Acide iocetamique [INN-French]
Acido iocetamico [INN-Spanish]
Acidum iocetamicum [INN-Latin]
HSDB 3344
EINECS 240-173-1
BRN 2171366
UNII-FA675Q0E3E
Cholebrine (TN)
NCGC00016720-01
CAS-16034-77-8
Iocetamic acid [USAN:USP:INN:BAN]
starbld0009604
Prestwick0_000838
Prestwick1_000838
Prestwick2_000838
Prestwick3_000838
IOCETAMIC ACID [MI]
SCHEMBL38499
BSPBio_000795
IOCETAMIC ACID [INN]
MLS002154025
IOCETAMIC ACID [HSDB]
SPBio_002716
IOCETAMIC ACID [VANDF]
BPBio1_000875
IOCETAMIC ACID [MART.]
CHEMBL1200770
IOCETAMIC ACID [WHO-DD]
CHEBI:91662
GSVQIUGOUKJHRC-UHFFFAOYSA-N
HMS1570H17
HMS2097H17
HMS2234P18
HMS3373O18
HMS3714H17
Tox21_110580
IOCETAMIC ACID [ORANGE BOOK]
CCG-220838
DB09403
NCGC00179430-01
NCGC00179430-04
SMR001233352
DB-347698
HY-107957
AB00513935
CS-0030997
NS00008882
D04563
EN300-18568455
SR-01000838894
Q6062203
SR-01000838894-2
BRD-A37492983-001-03-8
BRD-A37492983-001-10-3