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3-nitropyridin-2(1H)-one

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Identification
Molecular formula
C5H4N2O3
CAS number
36143-36-3
IUPAC name
3-nitro-1H-pyridin-2-one
State
State
At room temperature, 3-nitropyridin-2(1H)-one is a solid.
Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
138.11g/mol
Molar mass
138.1060g/mol
Density
1.4880g/cm3
Appearence

3-nitropyridin-2(1H)-one is typically a crystalline solid. The crystals are usually pale yellow in color, reflecting the presence of the nitro group which commonly imparts such coloration to organic compounds.

Comment on solubility

Solubility of 3-nitro-1H-pyridin-2-one

The solubility of 3-nitro-1H-pyridin-2-one, with the chemical formula C6H6N2O2, can be intriguing due to its specific structural characteristics. This compound generally exhibits the following solubility behaviors:

  • Polar solvents: 3-nitro-1H-pyridin-2-one tends to be soluble in polar solvents, such as water and alcohols, owing to the presence of the hydroxyl group (-OH) and nitro group (-NO2). These functional groups can engage in hydrogen bonding with solvent molecules.
  • Non-polar solvents: Meanwhile, its solubility in non-polar solvents is significantly limited. The aromatic nature of the pyridinic ring contributes to this characteristic behavior.
  • Temperature effects: The solubility may also vary with temperature; typically, an increase in temperature enhances the solubility of many organic compounds, including 3-nitro-1H-pyridin-2-one.

In conclusion, the solubility of 3-nitro-1H-pyridin-2-one is a vital aspect to consider when studying its applications and behavior in various chemical environments. It showcases how functional group interactions significantly influence a compound's affinity for different solvents.

Interesting facts

Interesting Facts about 3-Nitro-1H-pyridin-2-one

3-Nitro-1H-pyridin-2-one is a fascinating compound with a myriad of applications and properties that make it a noteworthy subject of study for chemists and researchers alike. Below are some intriguing aspects of this nitro-containing pyridine derivative:

  • Versatile Intermediate: This compound serves as a critical intermediate in the synthesis of various pharmaceuticals and agrochemicals, showcasing its utility in both medicinal and agricultural chemistry.
  • Biological Activity: Studies have shown that derivatives of 3-nitro-1H-pyridin-2-one possess potential biological activities, including antibacterial and antifungal properties, making them of interest in drug discovery and development.
  • Mechanistic Studies: The unique electronic structure of the nitro group adjacent to the pyridine ring facilitates interesting reactivity patterns, which are often explored in mechanistic organic chemistry studies.
  • Research Applications: This compound is used in various research projects, particularly in studying the reactivity of nitro compounds and exploring their potential environmental impacts.
  • Regioselectivity: The presence of the nitro group also affects the regioselectivity of subsequent reactions, allowing chemists to manipulate the compound for desired products selectively.

With such diverse applications and properties, 3-nitro-1H-pyridin-2-one is much more than just a chemical formula; it is a testament to the intricate relationships between structure and function in the realm of organic chemistry.

Synonyms
2-Hydroxy-3-nitropyridine
6332-56-5
3-Nitropyridin-2-ol
3-Nitro-2-pyridinol
2(1H)-Pyridinone, 3-nitro-
Pyridine, 2-hydroxy-3-nitro
2-PYRIDINOL, 3-NITRO-
EINECS 228-709-2
NSC 26281
3-NITRO-2(1H)-PYRIDINONE
DTXSID20212704
2-H-3-NPy
DTXCID10135195
2(1H)-Pyridinone, 3-nitro-(9CI)
228-709-2
3-nitropyridin-2(1H)-one
3-nitro-1H-pyridin-2-one
3-Nitro-2-hydroxypyridine
3-nitro-1,2-dihydropyridin-2-one
3-NITRO-2-OXOPYRIDINE
3-nitro-pyridin-2-ol
MFCD00006270
3-nitropyridone
nitro-pyridinone
NSC26281
3-Nitro-2-pyridone
2-hydroxy-3-nitropyridin
3-Nitro-2(1H)-pyridone
2-hydroxy-3-nitro pyridine
2-Hydroxy-3-nitro-pyridine
SCHEMBL244559
2(1H)-Pyridone, 3-nitro-
2-Hydroxy-3-nitropyridine, 98%
STR04579
BBL011064
NSC-26281
STK758373
STK802243
AKOS001736337
AKOS005254602
CS-W007868
FG-0494
GS-6877
PB30530
pyridine, 1,2-dihydro-3-nitro-2-oxo-
AC-16623
BP-10043
SY004633
DB-021174
DB-081272
H0999
NS00035416
EN300-57165
AG-227/06235005
AG-456/25001245
Z875018892
8PJ