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3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide

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Identification
Molecular formula
C14H13N3O8S2
CAS number
51949-48-1
IUPAC name
3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide
State
State

This compound is a solid at room temperature, typically existing as a powder or crystalline solid.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
411.39g/mol
Molar mass
411.3900g/mol
Density
1.5879g/cm3
Appearence

The compound appears as a yellowish crystalline solid, often characterized by the intensity of its color which is due to the presence of nitro groups.

Comment on solubility

Solubility of 3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide

The solubility of 3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide can be characterized by several key factors:

  • Solvent Interaction: This compound is likely to exhibit variable solubility in polar solvents due to the presence of sulfonamide groups, which generally enhance solubility in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules may significantly influence its solubility, making it more soluble in aqueous environments.
  • Structural Influence: The existence of nitro groups can also affect solubility. Nitro compounds are often polar and can increase solubility in polar solvents.
  • Solubility Trends: It is important to note that with compounds of such complexity, solubility can vary widely. Therefore, measurements of specific solubility in practical applications are crucial.

In summary, while predicting the exact solubility can be challenging without empirical data, analyzing structure and functional groups provides valuable insights into expected solubility behavior. Experimentation is key to determining practical solubility in both polar and nonpolar solvents.

Interesting facts

Interesting Facts about 3-Nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide

This compound is a fascinating example of the diverse functionalities that can be incorporated into a sulfonamide structure. Sulfonamides have been critical in medicinal chemistry, particularly due to their antimicrobial properties. Here are some compelling aspects of this compound:

  • Pharmacological Relevance: Sulfonamides, including this compound, have historically been used as antibacterial agents. Their mechanism often involves inhibiting bacterial growth by disrupting folate synthesis.
  • Structural Complexity: The presence of multiple nitro groups in the structure heightens its interest. Nitro groups can significantly influence the compound’s reactivity and biological activities, often enhancing its pharmacological profile.
  • Potential Applications: Beyond antimicrobial use, compounds boasting a robust sulfonamide framework may have applications in targeted drug design, particularly in the treatment of diseases where modulation of sulfur-containing compounds is beneficial.
  • Synthetic Pathways: The synthesis of such complex molecules involves multi-step reactions. Understanding these pathways can enhance knowledge of organic synthesis techniques and strategies for constructing intricate frameworks.

"The exploration of complex compounds like this opens doors to new possibilities in drug development and industrial chemistry."

Overall, 3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide represents a confluence of organic chemistry and medicinal application, inviting further research to unearth its full potential in therapeutic settings.

Synonyms
DINSED
96-62-8
Dinsedo
Di-m-nitrobenzenesulfonylethylenediamine
3-nitro-N-[2-[(3-nitrophenyl)sulfonylamino]ethyl]benzenesulfonamide
NSC-5109
P4KIO8KEG5
N,N'-(Ethane-1,2-diyl)bis(3-nitrobenzenesulfonamide)
N,N'-Ethylenebis(3-nitrobenzenesulfonamide)
DTXSID3046297
N,N'-Di(3-nitrobenzenesulfonyl)ethylenediamine
NCGC00160679-01
N,N'-Ethylenebis(m-nitrobenzenesulfonamide)
N,N'-Bis(3-nitrobenzenesulfonyl)ethylenediamine
N,N'-ethane-1,2-diylbis(3-nitrobenzenesulfonamide)
Benzenesulfonamide, N,N'-1,2-ethanediylbis(3-nitro-
DTXCID1026297
Dinsedum
CAS-96-62-8
N,N'-Ethylenebis[3-nitrobenzenesulfonamide]
N,N'-Ethylenebis[m-nitrobenzenesulfonamide]
N,N'-Bis[3-nitrobenzenesulfonyl]ethylenediamine
Dinsed [USAN:INN]
Dinsedum [INN-Latin]
Dinsedo [INN-Spanish]
UNII-P4KIO8KEG5
NSC 5109
Dinsed (USAN/INN)
DINSED [USAN]
DINSED [INN]
DINSED [MI]
Benzenesulfonamide, N,N'-ethylenebis(m-nitro-
SCHEMBL1814194
CHEMBL2104289
BENZENESULFONAMIDE,N,N'-1,2-ETHANEDIYLBIS[3-NITRO-
NSC5109
CHEBI:177610
MMDWBZHWHFGVHF-UHFFFAOYSA-N
AAA09662
Tox21_111982
STK241149
AKOS005421758
Tox21_111982_1
NCGC00160679-02
Benzenesulfonamide,N'-ethylenebis[3-nitro-
Benzenesulfonamide,N'-ethylenebis[m-nitro-
DS-010295
NS00123503
Benzenesulfonamide, N,N'-ethylenebis(3-nitro-
D03848
Benzenesulfonamide,N'-1,2-ethanediylbis[3-nitro-
Benzenesulfonamide,n,n-1,2-ethanediylbis[3-nitro-
SR-01000944700
N,N?-1,2-Ethanediylbis[3-nitrobenzenesulfonamide]
SR-01000944700-1
Q27286152
3-nitro-N-[2-[(3-nitrophenyl)sulonylamino]ethyl]benzenesulonamide