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3-Nitroacridin-9-amine

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Identification
Molecular formula
C13H9N3O2
CAS number
2209-38-5
IUPAC name
3-nitroacridin-9-amine
State
State

At room temperature, 3-Nitroacridin-9-amine is a solid. It retains its solid state under standard laboratory conditions without decomposing or sublimating.

Melting point (Celsius)
289.00
Melting point (Kelvin)
562.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
250.24g/mol
Molar mass
250.2390g/mol
Density
1.4210g/cm3
Appearence

3-Nitroacridin-9-amine typically appears as a yellow crystalline solid. Its bright color is characteristic of nitro compounds and is indicative of its chemical structure.

Comment on solubility

Solubility of 3-nitroacridin-9-amine

3-nitroacridin-9-amine, known for its unique chemical properties, presents interesting challenges and behaviors regarding its solubility:

  • Polar and Non-Polar Characteristics: Due to the presence of an amine group and a nitro group, 3-nitroacridin-9-amine exhibits both polar and non-polar characteristics, which can impact its solubility.
  • Solvent Interaction: This compound tends to dissolve well in organic solvents such as dichloromethane and ethanol, but may show limited solubility in water due to its relatively hydrophobic acridine framework.
  • Temperature Dependency: The solubility of 3-nitroacridin-9-amine may also vary with temperature; generally, increased temperatures can enhance solubility in organic solvents.
  • Concentration Effects: At higher concentrations, precipitation may occur, indicating a saturation point that is dependent on the specific solvent used.

As a guide, it is often noted that "Factors like temperature, solvent choice, and concentration significantly influence the solubility of organic compounds." Understanding these dynamics is essential for applications in synthesizing and utilizing 3-nitroacridin-9-amine.

Interesting facts

Interesting Facts about 3-Nitroacridin-9-amine

3-Nitroacridin-9-amine is a fascinating compound with significant implications in various fields, especially in pharmaceutical research and analytical chemistry. Here are some engaging points about this intriguing compound:

  • Structure & Properties: 3-Nitroacridin-9-amine is part of the acridine family, known for its heterocyclic structure which provides unique chemical properties. The presence of a nitro group significantly influences its reactivity and biological activity.
  • Biological Activity: Research has indicated that compounds like 3-nitroacridin-9-amine may possess antimicrobial and anticancer properties. It can serve as a lead compound for the development of new therapeutic agents.
  • Applications in Pharmacology: This compound is often studied for its potential use in drug development. Its ability to intercalate DNA suggests a mechanism by which it could inhibit cell division in cancerous cells.
  • Chemical Synthesis: The synthesis of 3-nitroacridin-9-amine typically involves multiple steps, showcasing the complexity and creativity inherent in organic chemistry. Understanding its synthesis can provide insights into structure-activity relationships that are crucial in medicinal chemistry.
  • Fluorescent Properties: Like many acridine derivatives, 3-nitroacridin-9-amine may exhibit fluorescence, making it useful in biochemical assays and studies involving DNA interactions.
  • Environmental Impacts: As with many synthetic compounds, it is essential to assess the environmental impact of 3-nitroacridin-9-amine, specifically its degradation products and transport within ecological systems.

In summary, 3-nitroacridin-9-amine stands out due to its unique structural attributes and potential biological applications. As scientists continue to explore its properties, it may pave the way for innovative solutions in the fields of medicine and environmental science.

Synonyms
3-nitroacridin-9-amine
ACRIDINE, 9-AMINO-3-NITRO-
14252-03-0
5-Amino-2-nitroacridine
BRN 0223845
6-nitro-9-aminoacridine
5-22-11-00048 (Beilstein Handbook Reference)
CHEMBL528704
SCHEMBL1504456
DTXSID40162070