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3-Nitrobenzenesulfonyl chloride

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Identification
Molecular formula
C6H4ClNO4S
CAS number
98-74-8
IUPAC name
3-nitrobenzenesulfonyl chloride
State
State

At room temperature, 3-nitrobenzenesulfonyl chloride is generally found in a solid state. Due to its crystalline nature, it is stable at normal temperatures and pressures, usually stored in a dry and cool place to prevent degradation.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
219.62g/mol
Molar mass
219.6230g/mol
Density
1.6350g/cm3
Appearence

3-Nitrobenzenesulfonyl chloride is typically a yellow to light brown solid. It may appear in crystalline form and is usually opaque. Its appearance can vary slightly depending on purity and specific sample conditions.

Comment on solubility

Solubility of 3-Nitrobenzenesulfonyl Chloride

3-Nitrobenzenesulfonyl chloride, known for its unique chemical structure, exhibits interesting solubility characteristics:

  • Polarity: The presence of the sulfonyl chloride group contributes to the polar nature of the compound, enhancing its solubility in polar solvents.
  • Solvent Compatibility: It is typically soluble in organic solvents such as dichloromethane, acetone, and ethyl acetate, due to its non-polar aromatic ring and polar functional groups.
  • Water Solubility: While 3-nitrobenzenesulfonyl chloride is not highly soluble in water, its reactivity with water to form sulfonic acids suggests limited interaction.
  • Temperature Effects: As with many chemical compounds, solubility can be influenced by temperature; increased temperatures often lead to higher solubility in organic solvents.

In summary, the solubility of 3-nitrobenzenesulfonyl chloride is primarily dictated by its polarity, solvent interactions, and external conditions. Its ability to dissolve in a variety of organic solvents makes it a valuable compound in synthetic chemistry.

Interesting facts

Interesting Facts about 3-Nitrobenzenesulfonyl Chloride

3-Nitrobenzenesulfonyl chloride, a fascinating compound, holds significant importance in the field of organic chemistry and pharmaceuticals. Here are some engaging facts about this compound:

  • Functional Group Versatility: This compound contains both a sulfonyl chloride group and a nitro group, which makes it a valuable intermediate for various chemical reactions, particularly in the synthesis of sulfonamide drugs.
  • Reactivity: The presence of the sulfonyl chloride group renders it highly reactive, facilitating nucleophilic substitution reactions. This property is utilized in creating a variety of other organic compounds.
  • Applications in Drug Development: 3-Nitrobenzenesulfonyl chloride is often used in pharmaceuticals to synthesize potential drug candidates. Sulfonamides, which can be derived from this compound, have been essential in the treatment of bacterial infections.
  • Research Tool: In laboratories, it serves as a tool for chemists to introduce or modify functional groups on aromatic rings, thereby aiding in the exploration of structure-activity relationships.
  • Environmental Considerations: While its industrial applications are numerous, handling and disposal of 3-nitrobenzenesulfonyl chloride should be done with caution due to its potential environmental impacts. Proper research into safe practices is essential.

As stated by renowned chemists, "The reactivity of sulfonyl chlorides opens new avenues for synthetic creativity.” This highlights the importance of compounds like 3-nitrobenzenesulfonyl chloride in expanding the boundaries of chemical synthesis.

In summary, this compound not only stands out for its unique chemical properties but also plays a pivotal role in advancing medicinal chemistry and organic synthesis.

Synonyms
3-Nitrobenzenesulfonyl chloride
121-51-7
3-nitrobenzene-1-sulfonyl chloride
Benzenesulfonyl chloride, 3-nitro-
3-Nitro-benzenesulfonyl chloride
3-Nitrophenylsulfonyl chloride
3-Nitrobenzenesulphonyl chloride
M-NITROBENZENESULFONYL CHLORIDE
m-Nitrophenylsulfonyl chloride
Benzenesulfonyl chloride, m-nitro-
KN1Z8WPL9U
M-NOSYL CHLORIDE
NSC 9806
NSC-9806
EINECS 204-476-2
MFCD00007435
m-nitrobenzene sulfonyl chloride
DTXSID6059526
3-(CHLOROSULFONYL)NITROBENZENE
NITROBENZENESULFONYL CHLORIDE, M-
UNII-KN1Z8WPL9U
3-Nitro-benzenesulfonylchloride
m-Nitrosulphonyl chloride
3-chlorosulfonylnitrobenzene
m-nitrobenzensulfonylchloride
SCHEMBL58443
3-Nitrobenzenesulfonylchloride
3-nitrobenzensulfonyl chloride
3-nitrobezenesulfonyl chloride
3-nitrophenylsulphonyl chloride
3-nitrophenyl-sulfonyl chloride
SCHEMBL2625180
3-Nitro benzenesulfonyl chloride
3-nitrobenzene sulfonyl chloride
DTXCID5033672
3-nitro-benzenesulphonyl chloride
3-nitrobenzene sulphonyl chloride
meta-nitrobenzenesulfonyl chloride
MWWNNNAOGWPTQY-UHFFFAOYSA-
NSC9806
3-nitro benzene sulphonyl chloride
3-nitro-1-benzenesulphonyl chloride
(3-nitro)-phenyl-sulphonyl chloride
m-nitrobenzene sulfonic acid chloride
STL199176
3-Nitrobenzenesulfonyl chloride, 97%
AKOS000119891
GS-3087
Benzenesulfonyl chloride, m-nitro-(8CI)
3-Nitrobenzenesulfonyl chloride, tech grade
A2561
N0143
NS00023962
EN300-17285
Q27282337
F0808-2029
InChI=1/C6H4ClNO4S/c7-13(11,12)6-3-1-2-5(4-6)8(9)10/h1-4H