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3-Nitrobenzoic acid

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Identification
Molecular formula
C7H5NO4
CAS number
121-92-6
IUPAC name
3-nitrobenzoic acid
State
State

3-Nitrobenzoic acid is a solid at room temperature, typically encountered as a crystalline powder. It is slightly soluble in water and more readily dissolves in organic solvents.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
167.12g/mol
Molar mass
167.1180g/mol
Density
1.5734g/cm3
Appearence

3-Nitrobenzoic acid appears as a pale yellow to light tan crystalline powder. The compound is known for its crystalline solid state, and its color can vary slightly depending on purity and specific conditions.

Comment on solubility

Solubility of 3-Nitrobenzoic Acid

3-Nitrobenzoic acid, with the chemical formula C7H5NO4, demonstrates interesting solubility characteristics that are essential for various applications in chemistry.

This compound is known to be:

  • Soluble in polar solvents: Particularly, it is well-soluble in water due to the presence of the carboxylic acid group, which can form hydrogen bonds.
  • Moderately soluble in organic solvents: It exhibits moderate solubility in alcohols and other polar organic solvents due to its aromatic structure and polar nitro group.
  • Insoluble in non-polar solvents: Solvents such as hexane or benzene show very little dissolution of 3-nitrobenzoic acid, as the lack of polar interactions prevents solvation.

As a general rule of thumb in chemistry, "like dissolves like," meaning that the polarity of the solvent plays a significant role in the solubility of a compound. In the case of 3-nitrobenzoic acid, the functionality of the acidic group greatly enhances its solubility profile in comparison to its non-polar counterparts.

Understanding the solubility of 3-nitrobenzoic acid is crucial for tasks such as:

  • **Synthesis** of new compounds
  • **Analytical applications** in various chemical assays
  • **Pharmaceutical formulations** where the solubility affects absorption

In conclusion, the solubility properties of 3-nitrobenzoic acid underline its versatility and significance in chemical processes.

Interesting facts

Interesting Facts about 3-Nitrobenzoic Acid

3-Nitrobenzoic acid is a fascinating aromatic compound that plays a significant role in both organic chemistry and various industrial applications. As a derivative of benzoic acid, this compound possesses a nitro group (-NO2) located at the meta position, which imparts unique properties and reactivity. Here are some intriguing aspects of 3-nitrobenzoic acid:

  • Precursor in Synthesis: It serves as a valuable starting material for synthesizing various important compounds, including pharmaceuticals and agrochemicals.
  • Regiochemistry: The meta-positioning of the nitro group allows for distinctive chemical behavior, making it an excellent candidate for studying substitution reactions.
  • Biological Activity: Researchers have explored its potential biological activity, particularly as a *potent inhibitor* of certain enzymes, opening avenues for therapeutic development.
  • Classical Condensation Reaction: It can undergo reactions such as the well-known Michael addition, showcasing its versatility in organic synthesis.
  • Environmental Chemistry: As an example of a nitroaromatic compound, it is often investigated for its environmental impact and degradation pathways.

Moreover, 3-nitrobenzoic acid can illustrate core principles in organic chemistry, such as electrophilic aromatic substitution and the effects of electron-withdrawing groups on reactivity. As noted by many chemists, "the study of substituted benzoic acids opens up a treasure trove of reactivity and applications." This resonates with the ongoing fascination that scientists have with *aromatic compounds*, which showcase a beautiful balance of stability and reactivity.

In summary, 3-nitrobenzoic acid is not just a solitary compound but a gateway to understanding broader chemical concepts and applications, making it a valuable subject of study in both academia and industry.

Synonyms
3-NITROBENZOIC ACID
121-92-6
m-Nitrobenzoic acid
Benzoic acid, 3-nitro-
Benzoic acid, m-nitro-
Metanitrobenzoic acid
3-Nitro-benzoic acid
m-Nitrobenzenecarboxylic acid
meta-Nitrobenzoic acid
MFCD00007251
CCRIS 2335
HSDB 6028
NSC 9801
EINECS 204-508-5
BRN 0908644
DTXSID0025737
UNII-H318ZW7612
AI3-09015
NSC-9801
H318ZW7612
M-CARBOXYNITROBENZENE
DTXCID605737
3-NITROBENZOIC ACID [HSDB]
CAS-121-92-6
meta-nitrobenzoate
mNitrobenzoic acid
Benzoic acid, mnitro
3-nitro benzoic acid
Benzoic acid, 3nitro
WLN: WNR CVQ
3-NITROBENZOICACID
mNitrobenzenecarboxylic acid
SCHEMBL132618
CHEMBL274839
SCHEMBL17347335
NSC9801
CHEBI:231494
BCP08709
HY-Y1313
STR01384
Tox21_201238
Tox21_303250
STK301724
3-Nitrobenzoic acid, puriss., 99%
AKOS000119012
AC-2834
CS-W020596
FN70301
PS-5143
NCGC00091521-01
NCGC00091521-02
NCGC00091521-03
NCGC00257168-01
NCGC00258790-01
3-Nitrobenzoic acid, ReagentPlus(R), 99%
N0154
NS00019769
BENZOIC ACID,3-NITRO MFC7 H5 N1 O4
EN300-18006
BENZOIC ACID,3-NITRO MFC7 H5 N1 O4
3-Nitrobenzoic acid, purum, >=98.0% (HPLC)
3-Nitrobenzoic acid, Vetec(TM) reagent grade, 98%
Q4634183
Z57127479
F2191-0133
204-508-5
27178-83-2