Skip to main content

3-Nitrobenzothiophene

ADVERTISEMENT
Identification
Molecular formula
C8H5NO2S
CAS number
1502-77-6
IUPAC name
3-nitrobenzothiophene
State
State

At room temperature, 3-Nitrobenzothiophene is a solid. It can be handled safely under normal laboratory conditions, taking necessary precautions for chemicals with a nitro group.

Melting point (Celsius)
55.00
Melting point (Kelvin)
328.15
Boiling point (Celsius)
347.00
Boiling point (Kelvin)
620.15
General information
Molecular weight
179.20g/mol
Molar mass
179.1980g/mol
Density
1.4300g/cm3
Appearence

3-Nitrobenzothiophene typically appears as a light brown solid. It is a chemical compound that combines a benzothiophene structure with a nitro group at the third position, giving it characteristic coloring and structure.

Comment on solubility

Solubility of 3-nitrobenzothiophene

3-nitrobenzothiophene, with its unique structure, exhibits interesting solubility characteristics that are vital for applications in various chemical processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is known to be soluble in organic solvents such as ethanol, acetone, and dichloromethane, making it suitable for reactions in non-aqueous environments.
  • Water Solubility: 3-nitrobenzothiophene demonstrates limited solubility in water due to its hydrophobic aromatic structure, which can be attributed to the presence of the thiophene ring and nitro group.
  • Temperature Effects: The solubility can vary with temperature; generally, increasing the temperature enhances solubility in organic solvents but has a minimal effect in water.
  • Concentration Impact: At higher concentrations, solubility may lead to precipitation, which is critical to consider in reaction preparations and product isolations.
  • Practical Implications: Understanding the solubility of 3-nitrobenzothiophene is crucial for applications in organic synthesis, materials science, and pharmaceuticals, where solvent choice can significantly influence reaction outcomes.

In conclusion, the solubility profile of 3-nitrobenzothiophene, characterized by its compatibility with organic solvents and limitations in aqueous solutions, is essential for optimizing its use in various chemical applications. As stated, "Solubility is the key to reactivity," and recognizing the solubility nature helps harness the compound's potential effectively.

Interesting facts

Exploring 3-Nitrobenzothiophene

3-Nitrobenzothiophene is a fascinating compound that merges elements of organic chemistry and environmental applications. This compound, which incorporates both a nitro group and a thiophene ring, showcases the versatility of aromatic compounds in various fields. Here are some intriguing facts about 3-nitrobenzothiophene:

  • Unique Structure: The fusion of nitrogen and sulfur in the structure of 3-nitrobenzothiophene contributes to its unique electronic properties, which can be crucial in the development of organic electronic materials.
  • Photography & Dyes: Compounds containing thiophene rings are often utilized in the manufacture of dyes and pigments. The stability and color properties of 3-nitrobenzothiophene make it a candidate for such applications.
  • Biological Interest: The presence of the nitro group can enhance biological activity, making this compound a subject of interest in medicinal chemistry for potential pharmaceutical development.
  • Environmental Impact: As with many nitro compounds, there is an interest in understanding the environmental behavior and degradation pathways of 3-nitrobenzothiophene, especially in polluted sites. This reflects the larger concern over nitroaromatic compounds in the ecosystem.
  • Reactivity: One notable characteristic of 3-nitrobenzothiophene is its reactivity under certain conditions, which can lead to the formation of useful derivatives for further exploration in synthetic chemistry.

In essence, the study of 3-nitrobenzothiophene is emblematic of the interdisciplinary nature of chemistry, straddling areas of synthetic methodology, environmental science, and potential therapeutic applications. Its characteristics open a window to numerous innovative research paths.

Synonyms
3-Nitrobenzo[b]thiophene
3-nitro-1-benzothiophene
3-Nitrobenzo(b)thiophene
9NY9BH3TLC
NSC-3747
NSC-48511
DTXSID3075125
DTXCID3035553
Benzo(b)thiophene, 3-nitro-(6CI,7CI,8CI,9CI)
17402-80-1
3-Nitrobenzothiophene
Benzo[b]thiophene, 3-nitro-
3-nitro-benzo[b]thiophene
Benzo(b)thiophene, 3-nitro-
MLS002637712
3-Nitrothianaphthene
Thianaphthene, 3-nitro-
3-Nitro benzothiophene
NSC 3747
BRN 0135966
AI3-18387
BENZOTHIOPHENE, 3-NITRO-
NSC3747
UNII-9NY9BH3TLC
3-?NitrobenZo[b]?thiophene
5-17-02-00013 (Beilstein Handbook Reference)
CHEMBL2138917
SCHEMBL10514704
SCHEMBL10818883
SCHEMBL28881962
HMS3085E17
NSC48511
MFCD00456545
AKOS000281696
SMR001547234
DB-064932
CS-0336846