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Propacetamide

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Identification
Molecular formula
C10H11NO2
CAS number
19686-73-8
IUPAC name
3-oxo-N-phenyl-butanamide
State
State

At room temperature, propacetamide is typically in a solid state.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.20
Boiling point (Celsius)
297.20
Boiling point (Kelvin)
570.30
General information
Molecular weight
177.21g/mol
Molar mass
177.2120g/mol
Density
1.0765g/cm3
Appearence

Propacetamide is a solid compound that can appear as a white crystalline powder under standard conditions. It is important to handle it in a properly ventilated area to avoid inhalation of dust.

Comment on solubility

Solubility of 3-oxo-N-phenyl-butanamide

The solubility of 3-oxo-N-phenyl-butanamide can be quite intriguing and depends on various factors such as temperature, pH, and the solvent used. In general, this compound exhibits moderate solubility in the following:

  • Polar solvents: It tends to dissolve well in polar aprotic solvents such as dimethyl sulfoxide (DMSO) and acetone, primarily due to its carbonyl functionality.
  • Organic solvents: Moderate solubility can also be observed in organic solvents like ethanol and methanol, although the presence of the phenyl group might limit its solubility somewhat.

However, it is less soluble in less polar solvents, such as hexane or petroleum ether, due to the hydrophobic characteristics of the phenyl ring. Thus, one would describe its solubility as:

  1. Higher solubility: In polar solvents and solvents capable of hydrogen bonding.
  2. Lower solubility: In non-polar solvents.

In conclusion, the solubility of 3-oxo-N-phenyl-butanamide is a balancing act between its polar and non-polar aspects, making it an interesting compound for various chemical applications.

Interesting facts

Exploring 3-Oxo-N-phenyl-butanamide

3-Oxo-N-phenyl-butanamide, also known as a member of the acylamide family, is a fascinating compound that blends functional versatility with intriguing chemical properties. Here are some compelling facts about this compound:

  • Chemical versatility: The presence of both a carbonyl group (ketone) and an amide renders it a useful building block in organic synthesis. This allows it to participate in various chemical reactions, making it important in pharmaceuticals and agrochemicals.
  • Pretreated pharmacological potential: Compounds similar to 3-oxo-N-phenyl-butanamide have been investigated for their biological activities, including anti-inflammatory and analgesic properties.
    The specific structure of 3-oxo-N-phenyl-butanamide may provide unique interactions with biological targets, paving the way for potential medicinal applications.
  • Environmental significance: Understanding compounds such as 3-oxo-N-phenyl-butanamide contributes to the wider field of environmental chemistry. As scientists study its degradation pathways, they can assess its impact and persistence in various ecosystems.

Notable Characteristics

This compound is not just another molecule; it embodies the intersection of several interesting scientific disciplines, including:

  • Organic Chemistry: Its structure showcases the principles of functional groups and is a prominent subject of study in the realm of organic transformations.
  • Medicinal Chemistry: Researchers can explore how modifications to its structure might enhance its drug-like properties.
  • Material Science: Insights into its properties can lead to innovations in the development of polymers and coatings.

In summary, 3-oxo-N-phenyl-butanamide is more than just a chemical entity; it is a portal into the complexities of organic synthesis and application in various fields of science. The ongoing study of such compounds is critical for advances in both industrial and medicinal chemistry.

Synonyms
ACETOACETANILIDE
102-01-2
3-Oxo-N-phenylbutanamide
Butanamide, 3-oxo-N-phenyl-
Acetoacetic anilide
Acetoacetamidobenzene
Acetylacetanilide
Acetoacetylaniline
N-Phenylacetoacetamide
Acetoacetanilid
Acetoacetic acid anilide
N-(Acetylacetyl)aniline
Acetanilide, 2-acetyl-
USAF EK-1239
beta-Ketobutyranilide
1-(Phenylcarbamoyl)-2-propanone
.alpha.-Acetylacetanilide
Anilid kyseliny acetoctove
((Acetoacetyl)amino)benzene
NSC 2656
alpha-Acetyl-N-phenylacetamide
CCRIS 4534
.alpha.-Acetyl-N-phenylacetamide
HSDB 2669
3-Oxo-N-phenylbutyramide
Anilid kyseliny acetoctove [Czech]
EINECS 202-996-4
W35JB9PY3X
DTXSID0024397
AI3-00854
Butanoic acid, 3-oxo-, amide, N-phenyl-
.beta.-Ketobutyranilide
NSC-2656
N-Phenyl-3-oxobutanamide
ACETOACETANILIDE [MI]
N-PHENYLACETYLACETAMIDE
N-(ACETOACETYL)ANILINE
ACETOACETANILIDE [HSDB]
DTXCID504397
.ALPHA.-KETOBUTYRANILIDE
EC 202-996-4
MFCD00008780
1-(PHENYLAMINO)-1,3-BUTANEDIONE
4-(PHENYLAMINO)-2,4-BUTANEDIONE
[(Acetoacetyl)amino]benzene
86349-51-1
1-(PHENYLAMINO)-1,3-1-(PHENYLCARBAMOYL)-2-PROPANONE
CAS-102-01-2
alpha-Acetylacetanilide
3-oxo-N-phenyl-butanamide
3-oxo-N-phenyl-butyramide
UNII-W35JB9PY3X
Acetoacetonilide
betaKetobutyranilide
2-acetylacetanilide
NPhenylacetoacetamide
3OxoNphenylbutanamide
ACETOACETAILIDE
Acetanilide, 2acetyl
Acetoacetylaminobenzene
N(Acetylacetyl)aniline
Butanamide, 3oxoNphenyl
alphaAcetylNphenylacetamide
N-Phenyl-3-ketobutanamide
Acetoacetanilide, >=98%
WLN: 1V1VMR
AcetessigsA currencyureanilid
ALPHA-KETOBUTYRANILIDE
1(Phenylcarbamoyl)2propanone
SCHEMBL14914
Acetoacetanilide, >=99.5%
alpha-acetyl-N-phenyl-acetamide
Butanamide, 3-oxo-N-phenyl-, labeled with carbon-14
CHEMBL1604429
NSC2656
STR00568
Tox21_201405
Tox21_303279
STK301287
Butanoic acid, 3oxo, amide, Nphenyl
AKOS000119678
FA38887
NCGC00091590-01
NCGC00091590-02
NCGC00091590-03
NCGC00257189-01
NCGC00258956-01
DB-318542
A0046
NS00003886
EN300-17592
F86391
Q15720542
Z56968279
F0001-0065
202-996-4