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(3-Phenyl-1,2,4-oxadiazol-5-yl)urea

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Identification
Molecular formula
C9H8N4O2
CAS number
478-49-9
IUPAC name
(3-phenyl-1,2,4-oxadiazol-5-yl)urea
State
State

At room temperature, (3-Phenyl-1,2,4-oxadiazol-5-yl)urea is in a solid state. It is stable under normal conditions and is commonly stored in airtight containers to prevent moisture uptake.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
344.00
Boiling point (Kelvin)
617.15
General information
Molecular weight
190.18g/mol
Molar mass
190.1670g/mol
Density
1.3287g/cm3
Appearence

(3-Phenyl-1,2,4-oxadiazol-5-yl)urea appears as a crystalline solid, typically white or off-white. It can be handled as a powder or crystalline substance, which is common for many organic compounds.

Comment on solubility

Solubility of (3-phenyl-1,2,4-oxadiazol-5-yl)urea

(3-phenyl-1,2,4-oxadiazol-5-yl)urea is a compound whose solubility can be influenced by various factors such as temperature, pH, and the presence of other solvents. The solubility characteristics of this compound are particularly noteworthy:

  • Polar vs. Nonpolar Solvents: Due to the presence of the urea functional group, which is polar, this compound may show reasonable solubility in polar solvents such as water and alcohols, while being less soluble in nonpolar solvents.
  • Temperature Dependency: Like many compounds, the solubility of (3-phenyl-1,2,4-oxadiazol-5-yl)urea usually increases with rising temperatures, providing greater kinetic energy and disrupting intermolecular interactions.
  • pH Effects: The solubility may also vary with the pH of the solution, as the ionization of the urea group can alter interactions with solvent molecules.

In general, understanding the solubility of (3-phenyl-1,2,4-oxadiazol-5-yl)urea is essential for its applications in various fields, and it's crucial to evaluate it under different conditions to predict its behavior in practical scenarios.

Interesting facts

Interesting Facts about (3-phenyl-1,2,4-oxadiazol-5-yl)urea

(3-phenyl-1,2,4-oxadiazol-5-yl)urea is a compound that showcases the fascinating interplay between organic chemistry and medicinal applications. This compound is particularly noteworthy for a few reasons:

  • Versatile Structure: The presence of the oxadiazole ring in its structure provides unique properties, allowing it to participate in various chemical reactions. The oxadiazole moiety is known for its ability to engage in hydrogen bonding and coordination with metals, which often enhances its reactivity.
  • Pharmacological Potential: Compounds containing oxadiazole derivatives have garnered attention in pharmaceutical research due to their potential anti-inflammatory, anti-tumor, and antimicrobial properties. There are ongoing studies investigating the biological activities associated with the substitution patterns in the phenyl group, which could influence the compound's efficacy.
  • Applications in Agriculture: Research indicates that derivatives of urea, including (3-phenyl-1,2,4-oxadiazol-5-yl)urea, can be used as herbicides or growth regulators. This opens up new avenues in agricultural chemistry where such compounds play a role in enhancing crop yield and protection against pests.
  • Photophysical Properties: The compound's structure allows it to exhibit interesting photophysical properties, making it a subject of interest for studies in luminescence and fluorescence. Researchers are exploring its use in organic light-emitting diodes (OLEDs) and other optoelectronic applications.

In summary, (3-phenyl-1,2,4-oxadiazol-5-yl)urea represents a fascinating example of how organic compounds can bridge the gap between theoretical chemistry and practical application. Its diverse range of properties and potential uses makes it a compound worth investigating in further detail.

Synonyms
5421-95-4
1,2,4-OXADIAZOLE, 3-PHENYL-5-UREIDO-
NSC 8177
FO6QB539UL
Urea, (3-phenyl-1,2,4-oxadiazol-5-yl)-
3-Phenyl-5-ureido-1,2,4-oxadiazole
BRN 0199954
NSC-8177
N-(3-Phenyl-1,2,4-oxadiazol-5-yl)urea
DTXSID80202560
4-27-00-08102 (Beilstein Handbook Reference)
UREA, N-(3-PHENYL-1,2,4-OXADIAZOL-5-YL)-
DTXCID10125051
Urea, (3-phenyl-1,2,4-oxadiazol-5-yl)-(8CI)
637-258-4
(3-phenyl-1,2,4-oxadiazol-5-yl)urea
1-(3-Phenyl-1,2,4-oxadiazol-5-yl)urea
NSC8177
UNII-FO6QB539UL
Urea,2,4-oxadiazol-5-yl)-
WLN: T5NO DNJ CMVZ ER
SCHEMBL14028304
3-Phenyl-5-ureido-1,4-oxadiazole
AKOS024332304
1,4-Oxadiazole, 3-phenyl-5-ureido-