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3-Phenyl-1,2,4-thiadiazol-5-amine

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Identification
Molecular formula
C8H7N3S
CAS number
3981-88-6
IUPAC name
3-phenyl-1,2,4-thiadiazol-5-amine
State
State

At room temperature, 3-Phenyl-1,2,4-thiadiazol-5-amine exists as a solid. It maintains its stability in a dry, enclosed container.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.15
General information
Molecular weight
177.23g/mol
Molar mass
177.2270g/mol
Density
1.3200g/cm3
Appearence

3-Phenyl-1,2,4-thiadiazol-5-amine appears as a crystalline solid powder. It typically exhibits a white to off-white color.

Comment on solubility

Solubility of 3-phenyl-1,2,4-thiadiazol-5-amine

The solubility of 3-phenyl-1,2,4-thiadiazol-5-amine is an important aspect to consider when evaluating its applications in various fields, particularly in pharmaceuticals and material sciences. This compound exhibits moderate solubility characteristics due to the presence of both hydrophobic and hydrophilic elements within its molecular structure.

Key Factors Influencing Solubility:

  • Functional Groups: The amine group can enhance solubility in polar solvents, while the phenyl ring contributes to hydrophobic interactions.
  • Solvent Characteristics: The solubility can vary significantly between different solvents. It is more soluble in polar protic solvents compared to non-polar solvents.
  • Temperature: Higher temperatures generally increase solubility for many organic compounds, and this is likely true for 3-phenyl-1,2,4-thiadiazol-5-amine.

For practical uses, the recommendation would be to test its solubility under various conditions to determine the optimal solvent for specific applications. In experimental setups, it’s essential to note that while the compound may exhibit some degree of solubility, its behavior in complex mixtures may differ. Therefore, careful assessment is crucial for successfully integrating 3-phenyl-1,2,4-thiadiazol-5-amine into formulations. As with many chemical compounds, solubility can play a pivotal role in chemical reactivity, bioavailability, and overall effectiveness in intended applications.

Interesting facts

Interesting Facts about 3-Phenyl-1,2,4-thiadiazol-5-amine

3-Phenyl-1,2,4-thiadiazol-5-amine, often referred to in scientific literature as a novel compound, holds significant importance in the field of medicinal chemistry and material sciences.

Key Features

  • Structural Versatility: The presence of the thiadiazole ring provides unique *electronic properties* that facilitate interactions with various biological targets.
  • Pharmacological Potential: This compound has been studied for its potential use in developing drugs against a variety of ailments, particularly due to the the amine group that can participate in hydrogen bonding.
  • Applications in Agriculture: Compounds similar to 3-phenyl-1,2,4-thiadiazol-5-amine are known for their use as pesticides and herbicides, illustrating its applicability in enhancing crop yield and protecting plants.

Scientific Significance

Researchers have noted that the diverse functionalities associated with the sulfur-containing ring structure can lead to exciting new avenues in drug formulation. As a result, derivative compounds are being synthesized and tested for their efficacy in therapeutic applications. One standout quality is the potential for modified derivatives to exhibit enhanced biological activity.

Moreover, 3-phenyl-1,2,4-thiadiazol-5-amine has gained attention for its role in material sciences, particularly regarding the synthesis of novel organic semiconductors. It has been integrated into organic light-emitting diodes (OLEDs) and organic photovoltaic cells, showcasing its importance beyond just biological applications.

Inspirational Impact

As a chemical scientist or student, engaging with compounds like 3-phenyl-1,2,4-thiadiazol-5-amine can spark curiosity and lead to further exploration. As one researcher aptly put it, "Each compound is a key to unlocking nature's secrets."
The combinatory nature of its intended applications showcases not only its *versatility* but also its potential to impact various fields positively.

Synonyms
3-PHENYL-1,2,4-THIADIAZOL-5-AMINE
17467-15-1
1,2,4-Thiadiazol-5-amine, 3-phenyl-
EINECS 241-485-0
NSC 119930
AI3-61472
DTXSID4066204
OYAHSBDYBOBAAQ-UHFFFAOYSA-
DTXCID7035567
InChI=1/C8H7N3S/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H,(H2,9,10,11)
OYAHSBDYBOBAAQ-UHFFFAOYSA-N
5-Amino-3-phenyl-1,2,4-thiadiazole
3-Phenyl-5-aminothiadiazole
3-Phenyl-5-amino-1,2,4-thiadiazole
1,2,4-Thiadiazole, 5-amino-3-phenyl-
MFCD00003159
3-Phenyl-1,2,4-thiadiazol-5-ylamine
CHEMBL47633
MLS002706954
NSC-119930
3-phenyl-1,2,4-thiadiazole-5-ylamine
1,2,4-Thiadiazol-5-amine,3-phenyl-
NSC119930
Maybridge1_002297
SCHEMBL69810
DivK1c_001049
SCHEMBL9095344
HMS548A09
M64KC294Z6
3-Phenyl-5-amino-1,4-thiadiazole
5-Amino-3-phenyl-1,4-thiadiazole
BDBM50595376
CCG-56129
SBB005511
STK517766
1,4-Thiadiazol-5-amine, 3-phenyl-
AKOS000813764
1,4-Thiadiazole, 5-amino-3-phenyl-
HA-0214
SDCCGMLS-0065894.P001
5-amino-3-phenyl-1,2,4,-thiadiazole
CDS1_000009
3-Phenyl-[1,2,4]thiadiazol-5-ylamine
SMR001574350
SY173551
DB-043984
NS00051718
ST45220961
3-Phenyl-1,2,4-thiadiazol-5(4H)-imine #
EN300-42973
F71615
SR-01000645108-1
F9995-0582
Z431702624