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3-Phenyl-3-propylazetidine

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Identification
Molecular formula
C13H19N
CAS number
161596-47-0
IUPAC name
3-phenyl-3-propyl-azetidine
State
State

At room temperature, 3-phenyl-3-propylazetidine is in the liquid state.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.20
Boiling point (Celsius)
225.50
Boiling point (Kelvin)
498.70
General information
Molecular weight
175.30g/mol
Molar mass
175.2700g/mol
Density
1.0100g/cm3
Appearence

3-Phenyl-3-propylazetidine is typically a pale yellow to colorless liquid. It is clear and may have a slight aromatic odor characteristic of azetidine derivatives.

Comment on solubility

Solubility of 3-phenyl-3-propyl-azetidine

3-phenyl-3-propyl-azetidine possesses interesting solubility characteristics due to its unique molecular structure. Here are some key points to consider:

  • Solvent Polarity: The solubility is significantly affected by the polarity of the solvent used. Generally, polar solvents may struggle to dissolve this compound, while non-polar solvents could enhance its solubility.
  • Hydrophobic Character: The presence of the bulky phenyl and propyl groups contributes to its overall hydrophobic character, which often leads to limited solubility in water.
  • Functional Groups: The azetidine ring can participate in hydrogen bonding, particularly in the presence of polar functional groups; however, the bulkiness of the substituents may hinder this interaction.
  • Temperature Influence: Like many organic compounds, solubility can increase with temperature, promoting greater dissolution in suitable solvents.

Overall, while C12H15N (3-phenyl-3-propyl-azetidine) may exhibit limited solubility in water, its compatibility with non-polar and certain organic solvents makes it a versatile compound in various applications. Understanding these solubility patterns is crucial for its effective use in chemical processes.

Interesting facts

Exploring 3-Phenyl-3-Propyl-Azetidine

3-Phenyl-3-propyl-azetidine is a fascinating compound that belongs to the class of cyclic amines, specifically a type of four-membered ring structure known as an azetidine. This compound showcases the intricate balance of structure and function in organic chemistry, allowing scientists to explore various applications in medicinal chemistry and material science.

Interesting Characteristics:

  • Cyclic Structure: The four-membered ring of azetidine imparts unique properties to the compound, which can influence its reactivity and stability. This is particularly interesting from a synthetic and medicinal chemistry perspective.
  • Phenyl Group: The presence of a phenyl substituent in the structure enhances the compound's ability to interact with biological targets, making it a subject of interest for drug development.
  • Potential Applications: As a versatile scaffold, 3-phenyl-3-propyl-azetidine may find utility in synthesizing pharmaceuticals, particularly in the realm of neurological and analgesic medications.
  • Synthetic Routes: The creation of azetidine derivatives like this one can often involve innovative synthetic methods, revealing exciting chemistry that students and professionals can explore.

As chemists continue to delve deeper into the properties and potential of compounds like 3-phenyl-3-propyl-azetidine, they illuminate the profound connections between molecular structure and biological activity. This compound stands as a vivid example of the dynamics at play within organic chemistry, encouraging an appreciation for the creativity and complexity inherent in the chemistry of life.

Synonyms
3-Phenyl-3-propylazetidine
AZETIDINE, 3-PHENYL-3-PROPYL-
L 1959
BRN 0131586
7215-20-5
DTXSID40222486
DTXCID40144977
4-20-00-03060 (beilstein handbook reference)
AKOS017515874