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3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole

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Identification
Molecular formula
C16H20N2O
CAS number
72748-35-5
IUPAC name
3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole
State
State
At room temperature, 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole is a solid, typically found in a crystalline or powdered form.
Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
268.35g/mol
Molar mass
268.3490g/mol
Density
1.1000g/cm3
Appearence

3-Phenyl-5-[1-(1-piperidyl)ethyl]isoxazole appears as a colorless or pale yellow solid. The compound is typically crystalline in nature and may sometimes be available in fine powder form.

Comment on solubility

Solubility of 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole

The solubility of 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole is influenced by several factors that determine how well this compound dissolves in various solvents. Understanding its solubility profile is crucial for applications in pharmaceuticals and chemical research.

Key Factors Affecting Solubility

  • Polarity: The molecular structure shows both polar and non-polar characteristics. This duality can affect its solubility in water versus organic solvents.
  • Temperature: Generally, an increase in temperature enhances solubility for solids. Thus, the dissolution process might be temperature dependent.
  • pH: If applicable, altering the pH of the solution can influence the ionization of functional groups, impacting solubility.
  • Solvent Type: Non-polar solvents may dissolve this compound better due to its hydrophobic regions, while polar solvents might struggle.

General Observations

Typically, compounds similar to 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole may show **limited solubility in water** but display good solubility in organic solvents such as ethanol or DMSO. This characteristic can be ascribed to the hydrophobic aryl group and the presence of piperidyl moiety, which enhances lipid solubility.

As stated, "Like dissolves like," and in this case, the balanced polarity suggests it might be more compatible with **lipophilic environments**. Thus, targeting the right solvent system is essential for practical applications and research involving this compound.

Interesting facts

Interesting Facts about 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole

3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole is a fascinating compound that stands out in the realm of medicinal chemistry. Here are some engaging insights into this unique chemical:

  • Structural Diversity: This compound contains an isoxazole ring, which is a five-membered heterocyclic compound renowned for its stability and diverse reactivity. The presence of the phenyl group enhances its pharmacological properties.
  • Pharmacological Potential: Compounds containing piperidine and isoxazole units have been studied for their potential therapeutic properties, including neuroprotective and anti-inflammatory effects. This suggests that 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole could be of interest in drug discovery.
  • Interaction with Biological Targets: The piperidyl moiety may enable the compound to interact with various neurotransmitter receptors in the brain, making it a candidate for further investigation in neuropharmacology.
  • Research Applications: Due to its structural features, scientists might explore this compound in various applications, including:
    1. Development of new analgesic agents
    2. Investigations into cognitive enhancers
    3. Potential use in treating psychiatric disorders

In summary, 3-phenyl-5-[1-(1-piperidyl)ethyl]isoxazole presents a blend of intriguing structural features and promising therapeutic potentials, driving interest in understanding its biochemical behavior. As the field of medicinal chemistry continues to evolve, compounds like this one could play essential roles in advancing healthcare solutions.