Skip to main content

3-Phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole;chloride

ADVERTISEMENT
Identification
Molecular formula
C17H21ClN2O
CAS number
309627-53-6
IUPAC name
3-phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole;chloride
State
State

This compound exists as a solid at room temperature.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
272.76g/mol
Molar mass
272.7600g/mol
Density
1.2000g/cm3
Appearence

The compound appears as a solid crystalline structure. The crystals are typically white to off-white in color.

Comment on solubility

Solubility of 3-phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole; chloride

The solubility of 3-phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole; chloride is an interesting area to explore due to its structural characteristics and ionic nature. This compound can be expected to have the following solubility traits:

  • Polarity: As a quaternary ammonium compound, the presence of the pyrrolidinium moiety increases polarity, which generally favors solubility in polar solvents such as water.
  • Ionic Interaction: The chloride ion enhances the solubility in aqueous solutions due to its ability to interact with water molecules, creating a more favorable environment for dissociation.
  • Solvent Dependence: While the salt form (chloride) is likely to be more soluble in water, solubility may vary considerably in organic solvents, where the phenyl group can influence solubility.
  • Temperature Influence: Like many salts, solubility could increase with temperature, making it crucial to consider thermal conditions during dissolution.

In summary, the solubility behavior of 3-phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole; chloride is characterized by its ionic nature and structure, with potential applications influenced by its solubility profile.

Interesting facts

Interesting Facts about 3-Phenyl-5-(2-Pyrrolidin-1-ium-1-ylethyl)isoxazole Chloride

3-Phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole chloride is a fascinating compound with unique properties and applications. Here are some intriguing facts about this compound:

  • Structural Significance: The presence of the isoxazole ring in this compound contributes to its reactivity and biological properties, highlighting the importance of heterocyclic compounds in medicinal chemistry.
  • Pharmacological Potential: Compounds like this one, which feature pyrrolidine moieties, are often associated with neuroactive properties and have been studied for their potential as antidepressants or analgesics.
  • Ionizable Group: The quaternary ammonium nature of the pyrrolidine group indicates that it is a charged species, which can influence its interaction with biological membranes and receptors, enhancing its bioavailability.
  • Chemistry in Action: The synthesis of this compound typically involves the reaction of a phenyl derivative with an appropriate isoxazole and pyrrolidine, showcasing the beauty of multi-component reactions in organic synthesis.
  • Research Applications: This compound serves as an intriguing subject in the study of drug design and development, particularly for targeting innovative therapeutic pathways.

The study of 3-phenyl-5-(2-pyrrolidin-1-ium-1-ylethyl)isoxazole chloride not only exemplifies the interdisciplinary nature of modern chemistry but also emphasizes the potential for developing novel compounds that address unmet medical needs. As research continues, this compound may pave the way for new therapeutic strategies.

Synonyms
Isoxazole, 5-(2-pyrrolidinoethyl)-3-phenyl-, hydrochloride
3-Phenyl-5-(2-pyrrolidinoethyl)isoxazole hydrochloride
ISOXAZOLE, 5-(2-PYRROLIDINYLETHYL)-3-PHENYL-, HYDROCHLORIDE
1087-04-3