3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole

Identification

Molecular formula

C₁₅H₁₈N₂O

CAS number

Not available

IUPAC name

3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole

State

At room temperature, 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole exists as a solid. It is usually found in a crystalline form, offering stability under standard conditions.

Melting point (Celsius)

98.50

Melting point (Kelvin)

371.65

Boiling point (Celsius)

360.65

Boiling point (Kelvin)

633.80

General information

Molecular weight

256.32g/mol

Molar mass

256.3170g/mol

Density

1.1740g/cm³

Appearence

The compound 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole typically appears as a crystalline solid. The crystals are often pale yellow to white in color, but this can vary depending on purity and form.

Comment on solubility

Solubility of 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole

The solubility of 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole is influenced by several factors, including its molecular structure and interactions with solvents. Here are some key points to consider:

Polar vs. Non-Polar Solvents: This compound may exhibit varying solubility in polar and non-polar solvents due to the presence of the isoxazole ring and the pyrrolidine moiety. Generally, compounds with polar functional groups are more soluble in polar solvents (e.g., water), while non-polar counterparts dissolve better in organic solvents (e.g., hexane).
Hydrogen Bonding: The isoxazole portion can engage in hydrogen bonding, potentially increasing solubility in polar solvents. This interaction is crucial as it can lead to higher solubility in solvent systems capable of forming such bonds.
Molecular Interactions: The phenyl group may influence the compound's overall solubility in organic solvents, as it can enhance π-π stacking interaction and contribute to solubility behavior based on solvent choice.
Temperature Dependency: Solubility could vary with temperature; like many organic compounds, increased temperature typically enhances solubility due to greater molecular motion.

In conclusion, while the precise solubility data for 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole may not be readily available, it is essential to consider the influence of the molecular structure on its solubility profile with regard to different solvents. Understanding these dynamics can prove beneficial for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole

3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole is a fascinating chemical compound that falls within the class of isoxazoles, which are known for their distinct five-membered ring structure containing both nitrogen and oxygen. This compound has garnered attention in various fields, particularly due to its potential pharmacological properties.

Key Attributes

Pharmacological Potential: The presence of both the isoxazole ring and the pyrrolidine moiety suggests possible interactions with biological systems, which may convey analgesic or anti-inflammatory effects.
Versatility in Chemistry: Isoxazoles are versatile intermediates in organic synthesis, allowing chemists to create diverse derivatives that can exhibit a range of activities.
Structural Importance: The phenyl group attached to the isoxazole contributes to the lipophilicity, potentially enhancing the compound's ability to cross biological membranes.

Studies have suggested that isoxazole derivatives can serve as bioactive molecules, which opens doors for developing new therapeutic agents. The unique combination of the aromatic ring with nitrogen-containing heterocycles like pyrrolidine offers exciting avenues for medicinal chemistry and drug design.

Furthermore, in the context of synthetic research, the formation of isoxazoles is often achieved through the innovative use of reactions such as the Beckmann rearrangement or other nitrogen-heteroatom coupling methods. This highlights the compound's relevance in modern synthetic organic chemistry, emphasizing both the creativity and complexity involved in its synthesis.

In summary, 3-phenyl-5-(2-pyrrolidin-1-ylethyl)isoxazole is not just a mere chemical formula; it encapsulates a world of potential that fuels ongoing research and inspires chemists to explore its capabilities and applications.