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3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole

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Identification
Molecular formula
C17H22N2O
CAS number
138564-60-0
IUPAC name
3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole
State
State

At room temperature, 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole is typically a solid. It retains its structural integrity and does not readily vaporize or dissolve under standard conditions.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
328.00
Boiling point (Kelvin)
601.15
General information
Molecular weight
286.39g/mol
Molar mass
286.3930g/mol
Density
1.1250g/cm3
Appearence

3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole typically appears as a colorless to pale yellow solid. It may form crystalline structures or an amorphous powder depending on its purity and specific preparation method.

Comment on solubility

Solubility of 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole

The solubility of 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole can be influenced by various factors, making it an interesting compound to consider.

Key Factors Affecting Solubility:

  • Polarity: As a semi-polar compound, its solubility in polar solvents like water may be limited. Typically, compounds that exhibit significant non-polar characteristics fare better in organic solvents.
  • Temperature: Increasing the temperature often enhances the solubility of organic compounds in solvents, which may apply to this isoxazole derivative.
  • pH Levels: The solubility of various compounds may also vary with changes in pH, so it is essential to consider the environment in which the compound is dissolved.

Research and empirical testing are crucial in determining the precise solubility characteristics of this compound. For practical applications, the compound may exhibit greater solubility in organic solvents compared to aqueous environments due to its structural attributes. In summary, while solubility specifics may still be under investigation, the context of its environment plays a vital role in its dissolution behavior.

Interesting facts

Interesting Facts about 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole

3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole is an intriguing compound that captures the attention of chemists and pharmacologists alike. Here are some fascinating insights:

  • Isoxazole Structure: This compound features an isoxazole ring, which is a five-membered aromatic ring containing two different heteroatoms, nitrogen and oxygen. This unique structure plays a crucial role in its biological activity.
  • Significance in Medicinal Chemistry: Compounds like this one have gained interest due to their potential as pharmacological agents. They may exhibit a variety of effects, including anti-inflammatory and neuroprotective properties, which make them suitable for drug development.
  • Piperidine Moiety: The presence of the piperidine ring can enhance the lipophilicity of the compound, potentially aiding in its ability to cross biological membranes and interact with targets within the body.
  • Activity against Neurological Disorders: Research indicates that related compounds may have implications in treating conditions such as anxiety and depression, pointing to the therapeutic potential of 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole.
  • Synthesis Pathways: The synthetic routes to develop this compound often involve advanced organic chemistry techniques, showcasing reactions such as cycloaddition and substitution that are pivotal in building the isoxazole framework.

As we continue to explore the chemical properties and potential applications of 3-phenyl-5-[3-(1-piperidyl)propyl]isoxazole, it remains a compelling topic of discussion in modern chemical research.

Synonyms
3-Phenyl-5-(3-(piperidin-1-yl)propyl)isoxazole
895-73-8
3-phenyl-5-(3-piperidin-1-ylpropyl)-1,2-oxazole
1-[3-(3-phenyl-1,2-oxazol-5-yl)propyl]piperidine