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3-(Phenyl)-5-(piperidinium-1-ylmethyl)isoxazolium chloride

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Identification
Molecular formula
C15H19ClN2O
CAS number
157654-67-6
IUPAC name
3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride
State
State
  • Solid: It exists as a crystalline solid at room temperature.
  • This compound is often handled in its solid powder form for ease of use in experimental settings.
Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
274.78g/mol
Molar mass
274.7790g/mol
Density
1.2000g/cm3
Appearence

The compound is usually found as a white to off-white crystalline solid, which may often appear as a powder. It has no marked or distinct odor.

Comment on solubility

Solubility of 3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride

The solubility of 3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride in various solvents is an important factor for its applications and behavior in different environments. Here are some key points regarding its solubility:

  • Water Solubility: Due to the presence of the +N (piperidinium) group, which is positively charged, this compound likely exhibits significant solubility in water, especially under conditions of higher temperatures.
  • Organic Solvent Compatibility: This compound may show varying solubility in organic solvents. Common solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) may dissolve the compound efficiently due to their polar and hydrogen-bonding capabilities.
  • pH Influence: The solubility can also be influenced by the pH of the solution, as the ionic nature can change with varying pH levels, affecting how well it interacts with water and other solvents.
  • Temperature Effects: As with many compounds, increasing temperature can enhance solubility, making it easier for the compound to dissolve in both polar and non-polar solvents.

In summary, the solubility of 3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride is a complex interplay of structural characteristics and environmental conditions, making it versatile for various scientific applications. Understanding this solubility is crucial for utilizing the compound effectively in research and practical applications.

Interesting facts

Interesting Facts about 3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride

This compound is an intriguing example in the field of medicinal chemistry, primarily due to its unique structure that combines both isoxazole and piperidine features. The isoxazole ring is notable for its stability and versatility, which allows the compound to exhibit a wide range of biological activities.

Key Highlights

  • Isoxazole Derivative: Isoxazoles are often investigated for their pharmacological potential, particularly in the context of central nervous system disorders. Their ability to modulate neurotransmitter systems has made them a subject of interest for drug development.
  • piperidine Moiety: The presence of the piperidin-1-ium group suggests that this compound may have quaternary ammonium characteristics. Such groups can enhance solubility and bioavailability, making it easier for the compound to traverse cell membranes.
  • Antimicrobial Research: Compounds with similar structures have been studied for their antimicrobial properties. Research into isoxazole derivatives often reveals potential uses as antifungal, antibacterial, or antiviral agents.
  • Ion Channel Modulation: Some studies imply that piperidine-based compounds can act as ion channel modulators. The interaction of this compound with ion channels could lead to novel therapeutic applications in treating various conditions.

Interestingly, the integration of both a phenyl group and a piperidine moiety may allow for enhanced interactions with biological targets, potentially leading to compounds with improved efficacy. Notably, the design and synthesis of such molecules can involve complex multi-step reactions, making it a rich area for exploration in organic synthesis.

Furthermore, as researchers investigate the pharmacodynamics and pharmacokinetics of such compounds, they often reveal unexpected therapeutic pathways and interactions. As modern medicinal chemistry evolves, compounds like 3-phenyl-5-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride could pave the way for new treatments and healthcare innovations.

Synonyms
3-Phenyl-5-(piperidinomethyl)isoxazole hydrochloride
1219-16-5
ISOXAZOLE, 3-PHENYL-5-(PIPERIDINOMETHYL)-, HYDROCHLORIDE