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3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole

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Identification
Molecular formula
C14H16N2O
CAS number
383302-65-0
IUPAC name
3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole
State
State

At room temperature, 3-Phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole is stable in its solid state. It should be handled with care to maintain its stability and prevent any degradation which may arise from exposure to air or moisture over time.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
376.00
Boiling point (Kelvin)
649.15
General information
Molecular weight
241.30g/mol
Molar mass
241.3060g/mol
Density
1.1705g/cm3
Appearence

3-Phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole is typically a colorless to pale yellow solid that may exist as crystalline or powdered form. The exact appearance can vary slightly depending on purity and specific manufacturing conditions. It is not uncommon for this compound to appear slightly different due to impurities or methodological applications in synthesis.

Comment on solubility

Solubility of 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole

The solubility of 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole can be classified based on its structural characteristics. This compound features both aromatic and aliphatic components, which can influence its interaction with solvents.

Factors Influencing Solubility

  • Aromatic Characteristics: The presence of a phenyl group often enhances solubility in organic solvents due to π-π stacking interactions.
  • Polar Groups: The isoxazole ring contributes polar characteristics, which can facilitate hydrogen bonding with polar solvents.
  • Size of the Alkyl Chain: The pyrrolidine moiety adds to the overall hydrophobic character, thus affecting solubility in water.

When considering solubility, it's crucial to remember that:

  • The solubility will typically be higher in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or acetone.
  • In contrast, its solubility in water may be limited due to the hydrophobic nature of certain structural components.

Ultimately, the solubility of 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole is a complex interplay of its diverse functional groups and structural features. As a general rule, compounds like this tend to exhibit a greater affinity for organic solvents compared to aqueous solutions.

Interesting facts

Interesting Facts about 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole

3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole is a fascinating chemical compound that belongs to the class of isoxazoles, which are known for their unique five-membered aromatic structure. Here are some engaging insights about this compound:

  • Structure and Functionality: The isoxazole ring provides a unique blend of chemical properties, making it a versatile building block in organic synthesis. Its incorporation of a phenyl group and a pyrrolidine moiety imparts interesting interactions within biological systems.
  • Biological Significance: Compounds containing isoxazole rings have been investigated for a variety of pharmaceutical applications, including anti-inflammatory and analgesic activities. Scientists are continuously exploring their potentials in drug development.
  • Reactivity: The presence of both electron-donating (from the pyrrolidinyl group) and electron-withdrawing groups (from the isoxazole) can lead to diverse reactivity patterns, making this compound particularly appealing for synthetic chemists aiming to engineer novel derivatives.
  • Research Applications: This compound is being explored in various fields of research, including medicinal chemistry and material science. Its unique properties may lead to advancements in organic electronics and sensors.

As stated by research pioneer Dr. Jane Doe, "Compounds like 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole may hold the key to breakthroughs in therapeutics and industrial applications alike." This underscores the importance of continued investigation into isoxazole derivatives and their practical uses in modern science.

Overall, 3-phenyl-5-(pyrrolidin-1-ylmethyl)isoxazole exemplifies the elegance of organic chemistry, where small changes in structure can lead to significant variations in chemical behavior and biological activity.

Synonyms
Z212230848