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Cinnamamide

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Identification
Molecular formula
C9H9NO
CAS number
538-42-1
IUPAC name
3-phenylprop-2-enamide
State
State
At room temperature, cinnamamide is solid, displaying the typical characteristics of an organic crystalline compound with a robust structure.
Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
429.20
Boiling point (Kelvin)
702.35
General information
Molecular weight
147.18g/mol
Molar mass
147.1750g/mol
Density
1.0843g/cm3
Appearence
Cinnamamide typically appears as a white to pale yellow crystalline solid. It tends to be free-flowing and can sometimes exhibit a waxy look depending on the purity and specific form. Under light, some samples may have a soft sheen or luster.
Comment on solubility

Solubility of 3-phenylprop-2-enamide

3-phenylprop-2-enamide, known for its aromatic character, exhibits a varied solubility profile that is influenced by several factors. When considering its solubility:

  • Solvent Polarity: The solubility of 3-phenylprop-2-enamide is greater in polar solvents such as ethanol and water, due to the ability of polar solvents to stabilize ionic or polar solutes.
  • Temperature: Generally, increasing temperature can enhance the solubility of organic compounds. In the case of 3-phenylprop-2-enamide, solubility improves with heat, making it more effective in higher temperature applications.
  • Concentration: At higher concentrations, saturation may occur, limiting further dissolution.

Interestingly, 3-phenylprop-2-enamide tends to show limited solubility in non-polar solvents, as it does not interact favorably with them. Therefore, it is crucial to select the appropriate solvent for effective use in reactions or formulations.

In summary, when working with 3-phenylprop-2-enamide, consider the following key points for optimal solubility:

  1. Utilize polar solvents for improved solubility.
  2. Monitor temperature for enhanced dissolution.
  3. Be cautious of concentration limits to avoid saturation.

Understanding these nuances can greatly impact the effectiveness of 3-phenylprop-2-enamide in various chemical contexts.

Interesting facts

Interesting Facts about 3-phenylprop-2-enamide

3-phenylprop-2-enamide, also known as cinnamamide, is a remarkable organic compound with several intriguing properties and applications. As a derivative of the well-known compound cinnamic acid, it holds a particular significance in both chemistry and biology.

Chemical Structure and Properties

  • Conjugated System: The structure features a conjugated double bond system that contributes to its chemical reactivity and stability.
  • Aromatic Ring: The phenyl group makes this compound particularly interesting due to the influence of aromaticity on its properties.

Biological Significance

This compound has attracted attention in the field of medicinal chemistry:

  • Potential Antimicrobial Activity: Studies suggest that 3-phenylprop-2-enamide exhibits antibacterial properties, which could lead to new avenues in antibiotic discovery.
  • Anti-inflammatory Effects: Preliminary research indicates it may possess anti-inflammatory effects, making it a candidate for further investigation in inflammatory diseases.

Versatile Applications

Beyond its biological applications, 3-phenylprop-2-enamide is useful in various chemical reactions:

  • Synthesis: It serves as a building block in organic synthesis, particularly in the design of more complex molecules.
  • Electrochemical Studies: Researchers are exploring its potential in electrochemistry, investigating how its properties can alter electrical conductance.

In summary, 3-phenylprop-2-enamide is more than just a chemical formula; its unique structure and properties lead to a multitude of scientific inquiries that keep researchers engaged in further exploration. As stated by one chemist, "The beauty of organic compounds lies not only in their structures but in the myriad of possibilities they present for discovery."

Synonyms
3-phenylprop-2-enamide
2-Propenamide, 3-phenyl-
DTXSID4060739
DTXCID8043234
Cinnamic Acid Amide
SCHEMBL159753
SCHEMBL1821026
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AKOS022259532
SY006676
DB-054088
Q204165