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3-Phenylprop-2-enehydroxamic acid

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Identification
Molecular formula
C9H9NO2
CAS number
1069-70-8
IUPAC name
3-phenylprop-2-enehydroxamic acid
State
State

At room temperature, 3-Phenylprop-2-enehydroxamic acid is typically found in a solid state, presenting itself as a stable crystalline powder.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.00
Boiling point (Celsius)
329.00
Boiling point (Kelvin)
602.00
General information
Molecular weight
167.19g/mol
Molar mass
167.1880g/mol
Density
1.1030g/cm3
Appearence

3-Phenylprop-2-enehydroxamic acid typically appears as a crystalline solid. Its color ranges from white to off-white and it possesses a mild to non-distinct odor. The compound is often used in chemical research and industrial applications.

Comment on solubility

Solubility of 3-phenylprop-2-enehydroxamic acid

3-phenylprop-2-enehydroxamic acid (C10H11NO2) exhibits distinctive solubility characteristics that make it notable in various chemical contexts. The solubility of this compound can be influenced by multiple factors, including:

  • Polarity: This compound contains both hydroxamic acid functionality and an aromatic phenyl group, leading to a polar structure.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents (like water or alcohols) due to its hydroxamic acid group, which can form hydrogen bonds with the solvent.
  • pH Dependence: The solubility might vary significantly with changes in pH; under acidic conditions, the hydroxamic acid can remain protonated, affecting solute-solvent interactions.
  • Temperature Effects: Increased temperature typically enhances solubility for many organic compounds, making thermal conditions an essential factor in dissolution behavior.

Overall, while the detailed solubility profile can depend on specific experimental conditions, 3-phenylprop-2-enehydroxamic acid is expected to demonstrate reasonable solubility in polar environments, primarily due to its functional groups.

Interesting facts

Interesting Facts About 3-Phenylprop-2-enehydroxamic Acid

3-Phenylprop-2-enehydroxamic acid, often recognized for its unique structural characteristics, plays a significant role in various fields of chemistry and biology. Here are some interesting aspects of this intriguing compound:

  • Structure and Functionality: This compound features a phenyl group attached to a propene backbone, coupled with a hydroxamic acid functional group. This structure contributes to its unique reactivity and potential biological applications.
  • Biological Activity: Hydroxamic acids, including 3-phenylprop-2-enehydroxamic acid, are known for their ability to inhibit metalloproteinases. These enzymes are crucial for various physiological processes, including tissue remodeling and wound healing. Consequently, compounds like these are explored for their potential therapeutic effects.
  • Synthesis: The synthesis of 3-phenylprop-2-enehydroxamic acid can be achieved via various methods, often involving the reaction of corresponding amines with hydroxycarboxylic acids. This illustrates the compound's accessibility for research and development in academic and industrial chemistry.
  • Applications in Research: Researchers utilize 3-phenylprop-2-enehydroxamic acid in drug design and molecular biology studies. Its ability to modify enzyme activity makes it a valuable tool in understanding complex biochemical pathways.
  • Potential in Medicinal Chemistry: The therapeutic potential of hydroxamic acids is under investigation in treating diseases related to inflammation and cancer. 3-Phenylprop-2-enehydroxamic acid may contribute to this exploratory landscape as a lead compound.

As we delve deeper into the world of chemical compounds, the unique features and potential applications of substances like 3-phenylprop-2-enehydroxamic acid remind us of the enormous possibilities that exist within the realm of chemistry. Scientific exploration and ingenuity continue to unlock new understandings and uses for such compounds in health and industry.

Synonyms
N-hydroxy-3-phenylprop-2-enamide
NS00125823