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3-Phenylpropylamine

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Identification
Molecular formula
C9H13N
CAS number
2038-57-5
IUPAC name
3-phenylpropan-1-amine
State
State
Under normal conditions, 3-Phenylpropylamine is a liquid.
Melting point (Celsius)
-24.00
Melting point (Kelvin)
249.15
Boiling point (Celsius)
204.40
Boiling point (Kelvin)
477.55
General information
Molecular weight
135.21g/mol
Molar mass
135.2060g/mol
Density
0.9247g/cm3
Appearence
3-Phenylpropylamine is a clear, colorless to pale yellow liquid with a characteristic amine odor. It can exhibit slight color variations depending on its purity and exposure to air and light, which sometimes causes a yellowish tint.
Comment on solubility

Solubility of 3-phenylpropan-1-amine

The solubility of 3-phenylpropan-1-amine in various solvents is influenced by its molecular structure and functional groups. This compound can exhibit different solubility properties:

  • In Water: 3-phenylpropan-1-amine is generally moderately soluble in water due to the presence of the amine (-NH2) functional group, which can form hydrogen bonds with water molecules.
  • In Organic Solvents: It shows a higher solubility in organic solvents such as ethanol, methanol, and acetone. This is attributed to its hydrophobic phenyl group, which enhances solubility in nonpolar to slightly polar solvents.
  • Temperature Impact: Like many organic compounds, the solubility of 3-phenylpropan-1-amine tends to increase with temperature, allowing for better dissolution in both water and organic solvents.

In summary, the solubility of 3-phenylpropan-1-amine can be described as:

  1. Moderately soluble in water, due to its amine group.
  2. Soluble in organic solvents, making it versatile for various applications.
  3. Temperature-dependence is a key factor affecting solubility.

Understanding the solubility behavior is essential for applications in pharmaceuticals and chemical processes, where solubility can impact reactivity, formulation, and bioavailability.

Interesting facts

Exploring 3-Phenylpropan-1-amine

3-Phenylpropan-1-amine, also known as β-phenylpropylamine, is a fascinating organic compound that falls under the category of amines. This compound captures attention due to its unique structure and potential applications. Here are some interesting facts:

Key Features:

  • Synthesized from: It can be synthesized through the reduction of β-phenylpropanal, providing a pathway for the creation of various derivatives.
  • Industrial Relevance: 3-Phenylpropan-1-amine is relevant in the synthesis of pharmaceutical compounds, particularly those aimed at treating various CNS disorders.
  • Physiological Importance: It is structurally similar to naturally occurring neurotransmitters, which suggests its potential role in neurological research.

Research and Applications:

Researchers are particularly interested in this compound for several reasons:

  • Neuropharmacology: Studying its interaction with neurotransmitter receptors can shed light on its behavior in the central nervous system.
  • Chiral Chemistry: 3-Phenylpropan-1-amine can participate in enantioselective reactions, making it valuable for the production of chiral drugs.
  • Starting Material: It serves as an important precursor in organic synthesis, offering versatility in the development of novel therapeutic agents.

"The exploration of amines and their derivatives opens new horizons in chemistry, paving the way for innovative treatments and compounds." This quote encapsulates the excitement surrounding 3-phenylpropan-1-amine and its role in advancing medicinal chemistry.

Overall, 3-phenylpropan-1-amine exemplifies the integral connection between chemical structure and biological function, showcasing the importance of understanding such compounds in advancing scientific knowledge and improving health outcomes.

Synonyms
3-Phenylpropylamine
2038-57-5
3-phenylpropan-1-amine
Benzenepropanamine
3-Phenyl-1-propylamine
1-Amino-3-phenylpropane
Hydrocinnamylamine
3-Phenyl-n-propylamine
gamma-Phenylpropylamine
3-phenylpropanamine
3-Phenyl-1-propanamine
gamma-Phenyl-n-propylamine
PROPYLAMINE, 3-PHENYL-
3-Phenyl-1-aminopropane
.gamma.-Phenylpropylamine
3-aminopropylbenzene
.gamma.-Phenyl-n-propylamine
NSC 87080
EINECS 218-012-1
BRN 2205526
P8326EZ31P
NSC-87080
PROPYLAMINE, 3-PHENYL
CHEBI:45017
DTXSID10174307
4-12-00-02625 (Beilstein Handbook Reference)
3Phenylnpropylamine
3Phenyl1propanamine
1Amino3phenylpropane
gammaPhenylpropylamine
Propylamine, 3phenyl
gammaPhenylnpropylamine
Benzenepropanamine (9CI)
DTXCID8096798
218-012-1
3-Phenyl-propylamine
MFCD00008224
phenylpropylamine
gamma-Aminopropylbenzene
CHEMBL276864
PROPYLAMINE, 3-PHENYL-, HYDROCHLORIDE
UNII-P8326EZ31P
phenylpropyl amine
1tnk
1utl
3-Phenylproylamine
3-phenylpropylarnine
?-Aminopropylbenzene
3-phenyl propylamine
3-phenylpropyl-amine
(3-phenylpropyl)amine
3-phenyl propyl amine
3-phenyl-propyl-amine
1-phenyl-3-propylamine
benzene, (3-amino)propyl-
NCIOpen2_001106
SCHEMBL52482
3-Phenyl-1-propylamine, 98%
NSC87080
BDBM50113826
STK825996
AKOS000120432
AB00940
DB04410
PS-5335
s10208
PD016298
SY049659
DB-045192
NS00026610
P0664
EN300-20467
Q23978199
F2190-0400
Z104478312
InChI=1/C9H13N/c10-8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8,10H