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3-(Propylamino)indol-2-one

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Identification
Molecular formula
C11H14N2O
CAS number
40519-94-8
IUPAC name
3-(propylamino)indol-2-one
State
State

At room temperature, 3-(Propylamino)indol-2-one is typically a solid. This compound is stable under standard conditions and does not have significant vapor pressure at room temperature.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.15
General information
Molecular weight
202.27g/mol
Molar mass
202.2690g/mol
Density
1.2364g/cm3
Appearence

3-(Propylamino)indol-2-one typically appears as a solid. The precise color and texture may vary, but indol-2-one derivatives are often observed as crystalline solids. The appearance can range from off-white to pale yellow depending on purity and specific structure modifications, such as substituents and the presence of impurities.

Comment on solubility

Solubility of 3-(Propylamino)indol-2-one

The solubility of 3-(propylamino)indol-2-one is a captivating topic due to its potential implications in various applications. This compound features a distinctive structure that influences its solubility characteristics in different solvents.

Factors Influencing Solubility

The solubility of this compound can be significantly affected by several factors:

  • Polarity: Being an indole derivative, the presence of the propylamino group may contribute to an increase in the polarity of the molecule, thereby enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds through the amino group can further facilitate solubility in polar environments.
  • pH Levels: Changes in pH may alter the ionization state of the amino group, which can impact solubility—often resulting in greater solubility at higher or lower pH levels.

Solvent Compatibility

When considering solvent compatibility for 3-(propylamino)indol-2-one, it is essential to note:

  • Good solubility is likely in organic solvents such as ethanol and methanol.
  • Moderate solubility is expected in dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
  • Less solubility may be observed in non-polar solvents like hexane.

In conclusion, understanding the solubility of 3-(propylamino)indol-2-one is crucial for its use in real-world applications, as solubility dictates its efficacy and behavior in biological systems and chemical environments. Investigating and optimizing solubility can lead to improved reaction yields and the overall performance of this intriguing compound.

Interesting facts

Discovering 3-(Propylamino)indol-2-one

3-(Propylamino)indol-2-one, often referred to in scientific literature for its intriguing structural characteristics, is a compound that merges aspects of both medicinal chemistry and organic synthesis. This compound serves as a vital scaffold in the design of various bioactive molecules.

Key Highlights:

  • Biological Significance: 3-(Propylamino)indol-2-one derivatives have been studied for their potential pharmacological properties, including **anti-cancer** and **anti-inflammatory** activities.
  • Synthetic Versatility: The indole structure is known for its adaptability in chemical reactions, allowing chemists to modify it easily and explore diverse functionalization pathways.
  • Natural Occurrences: Indole and its derivatives are commonly found in a variety of natural compounds, including alkaloids, indicating their significance in nature and biology.
  • Potential Applications: Compounds related to 3-(propylamino)indol-2-one have been investigated in the context of developing novel therapeutic agents for various diseases, making it a focus of rejuvenating research efforts.

As a chemistry student, understanding the properties and implications of this compound can unveil pathways for innovative medicinal applications. The interconnectedness of its structure with biological activity offers a rich field for exploration and discovery.

Conclusion

In summary, 3-(Propylamino)indol-2-one stands as a testament to the exciting relationship between organic chemistry and pharmacology. Its contributions to the development of medicinal compounds exemplify the pivotal role that chemical research plays in advancing healthcare solutions. As stated by renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” Exploring compounds like these continuously opens new doors to science and innovation.