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3-Propylidenephthalide

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Identification
Molecular formula
C12H12O2
CAS number
1095-99-6
IUPAC name
3-propylideneisobenzofuran-1-one
State
State
At room temperature, 3-Propylidenephthalide is typically found in a solid state. It is crystalline in nature.
Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
188.22g/mol
Molar mass
188.2210g/mol
Density
1.1550g/cm3
Appearence
3-Propylidenephthalide appears as a solid, crystalline substance. It has a pale yellow color and can have a faint pleasant odor depending on its purity and specific conditions.
Comment on solubility

Solubility of 3-propylideneisobenzofuran-1-one

The solubility of 3-propylideneisobenzofuran-1-one is an interesting topic, as it presents a unique profile due to its complex structure. This compound generally exhibits:

  • Low solubility in water: Due to its hydrophobic characteristics, 3-propylideneisobenzofuran-1-one tends to be poorly soluble in aqueous environments.
  • Increased solubility in organic solvents: It is more readily soluble in non-polar and slightly polar organic solvents such as dichloromethane, ethyl acetate, and chloroform.
  • Dependence on temperature: As with many organic compounds, solubility can significantly change with temperature; typically, solubility in organic solvents increases at higher temperatures.

Understanding its solubility is critical for practical applications. In various chemical processes, accurate solubility data can assist in:

  1. Extraction procedures: Solvent selection based on the solubility characteristics can enhance the efficiency of extraction methods.
  2. Synthesis reactions: Knowing how 3-propylideneisobenzofuran-1-one interacts with solvents can optimize conditions for successful synthesis.
  3. Formulation in products: For using this compound in formulations, especially in pharmaceuticals or agrochemicals, solubility aids in determining the appropriate delivery methods.

In summary, while 3-propylideneisobenzofuran-1-one may present limitations in aqueous solutions, its solubility in organic solvents opens up diverse applications within various fields of chemistry.

Interesting facts

Interesting Facts about 3-Propylideneisobenzofuran-1-one

3-Propylideneisobenzofuran-1-one, often referred to as a unique member of the benzofuran family, presents several intriguing aspects worth discussing:

  • Chemical Structure: The structure of 3-propylideneisobenzofuran-1-one includes a benzofuran core that is fused with a propylidene group, which is responsible for its distinct properties. The arrangement of the double bonds in the compound contributes to its reactivity and potential applications.
  • Natural Product Potential: This compound structure resembles those found in various natural products, suggesting that it may occur in nature or serve as a precursor for the synthesis of more complex compounds. Chemists are often inspired by natural substances when designing new materials.
  • Applications: Compounds of this nature could have implications in pharmaceuticals and materials science. They may possess interesting biological activities, which highlight the importance of studying such compounds: potential applications range from agricultural to medicinal chemistry.
  • Reactivity: The presence of the furan ring can make the compound susceptible to electrophilic reactions, potentially allowing for functionalization that can lead to more complex derivatives.
  • Research Interest: As chemists continue to explore the properties of various benzofuran derivatives, 3-propylideneisobenzofuran-1-one may garner attention for its unique structure and the insights it can provide regarding the structure-activity relationship in related compounds.

In conclusion, 3-propylideneisobenzofuran-1-one embodies a fascinating intersection of structure and function that invites further investigation. As research progresses, the roles such compounds play in natural systems and synthetic chemistry will likely broaden, making them a significant focus for those in the field.

Synonyms
17369-59-4
3-PROPYLIDENEPHTHALIDE
Propylidene phthalide
DTXSID7025972
Propylidenephthalide
FEMA No. 2952
WHD8YJ226P
DTXCID70810032
241-402-8
1(3H)-Isobenzofuranone, 3-propylidene-
Phthalide, 3-propylidene-
3-propylidene-1,3-dihydro-2-benzofuran-1-one
3-propylideneisobenzofuran-1-one
MFCD00051813
3-propylidene-2-benzofuran-1-one
(3Z)-3-propylidene-1,3-dihydro-2-benzofuran-1-one
Butylphthalide Impurity 19
SCHEMBL317445
SCHEMBL11045364
SCHEMBL11045365
SCHEMBL11045384
SCHEMBL30234042
AKOS030229038
SY057383
DB-043953
NS00100392