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3-(Pyrrolidin-1-ylmethyl)-1H-indol-5-amine

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Identification
Molecular formula
C13H17N3
CAS number
.3
IUPAC name
3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine
State
State

This compound is typically found in a solid state at room temperature, characterized by a stable form that is suitable for various chemical applications.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
486.20
Boiling point (Kelvin)
759.20
General information
Molecular weight
214.30g/mol
Molar mass
214.2920g/mol
Density
1.2230g/cm3
Appearence

3-(Pyrrolidin-1-ylmethyl)-1H-indol-5-amine typically appears as a solid compound. Its color may range depending on its purity, from off-white to pale yellow.

Comment on solubility

Solubility of 3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine

The solubility of 3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine can be influenced by various factors including its molecular structure, polarity, and the presence of functional groups. Here are some key points to consider:

  • Polarity: The presence of the pyrrolidine group can contribute to the solubility in polar solvents, while the indole structure might also interact with hydrophobic environments.
  • Solvent Type: This compound tends to be more soluble in polar protic solvents such as water and alcohols, compared to non-polar solvents like hexane.
  • pH Effect: The solubility may be pH-dependent, as the amine group can become protonated under acidic conditions, potentially increasing its solubility.
  • Temperature Influence: Increasing temperature usually enhances solubility for many compounds, including this amine, due to increased molecular motion.

In summary, the solubility of 3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine is a multi-faceted topic, leading to diverse solubility profiles based on the surrounding conditions and solvent characteristics. As I always say, "Understanding solubility is key to unlocking the potential of chemical compounds!"

Interesting facts

Interesting Facts about 3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine

3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine, often abbreviated in scientific literature as 3-PMA, is a fascinating compound that belongs to the broader family of indole derivatives. These compounds are known for their diverse range of biological activities, making them a subject of intense study in the field of medicinal chemistry.

Biological Significance

This compound has garnered attention due to its potential role in various pharmacological applications. Here are some points illuminating its importance:

  • Neurotransmitter Modulation: 3-PMA is believed to influence neurotransmitter systems in the brain, which could have implications for mood regulation and cognitive function.
  • Antidepressant Potential: Preliminary studies suggest that similar indole derivatives may exhibit antidepressant properties, opening avenues for new therapeutic agents.
  • Research in Anti-cancer Treatments: The indole structure is a known scaffold in many anti-cancer agents, as it can interact with cellular pathways involved in cancer progression.

Chemical Properties and Synthesis

3-PMA is noteworthy for its unique structural components. The presence of the pyrrolidine ring introduces interesting steric and electronic properties that can influence its reactivity and interaction with biological targets. Below are some thoughts on its synthesis:

  • Synthetic routes often involve multistep reactions, showcasing the creativity required in organic chemistry to create such complex structures.
  • The use of specific catalysts can enhance yield and selectivity, demonstrating the precision needed in modern synthetic techniques.

Conclusion

Overall, 3-(pyrrolidin-1-ylmethyl)-1H-indol-5-amine stands out as an important compound in the realm of chemical research, particularly within the context of developing new medications. As scientists continue to explore its properties, we might uncover further applications that could impact health and wellness. As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." The exploration of compounds like 3-PMA is a testament to this philosophy, where each discovery leads to new possibilities!

Synonyms
3414-75-3
INDOLE, 5-AMINO-3-(1-PYRROLIDINYLMETHYL)-
BRN 0401173
5-Amino-3-(pyrrolidinomethyl) indole
3-(1-Pyrrolidinylmethyl)-1H-indol-5-amine
DTXSID90187738