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3-(2-Pyrrolidinyl)indole

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Identification
Molecular formula
C12H14N2
CAS number
2218-07-9
IUPAC name
3-pyrrolidin-2-yl-1H-indole
State
State

At room temperature, this compound exists as a solid, indicating strong intermolecular forces in its structure.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
405.30
Boiling point (Kelvin)
678.45
General information
Molecular weight
172.25g/mol
Molar mass
172.2480g/mol
Density
1.2000g/cm3
Appearence

The compound typically appears as a white to off-white crystalline solid. It exhibits a consistent crystalline structure and is often used in its pure form for various applications in research settings.

Comment on solubility

Solubility of 3-pyrrolidin-2-yl-1H-indole

The solubility characteristics of 3-pyrrolidin-2-yl-1H-indole can be quite intriguing and are influenced by several factors:

  • Polarity: The presence of a pyrrolidine ring contributes to the molecule's overall polarity, which can enhance its solubility in polar solvents.
  • Solvent Choices: This compound is generally more soluble in solvents such as ethanol, methanol, and water, rather than in non-polar solvents like hexane.
  • Temperature Influence: Solubility tends to increase with temperature, making hot solvent conditions more favorable for dissolving 3-pyrrolidin-2-yl-1H-indole.
  • pH Sensitivity: The solubility can be pH-dependent, which means altering the pH of the solution may either enhance or hinder the solubility.

Understanding the solubility of this compound is crucial for applications in pharmaceuticals and chemical synthesis processes. As one must remember, the ability of a substance to dissolve is often a key factor in its bioavailability and efficacy in various applications.

Interesting facts

Interesting Facts about 3-pyrrolidin-2-yl-1H-indole

3-pyrrolidin-2-yl-1H-indole is a fascinating heterocyclic compound with unique properties and potential applications. Its structure features a combination of an indole ring system and a pyrrolidine moiety, making it a key molecule in various fields of research.

Chemical Significance

  • Bioactivity: Compounds with indole structures are known for their biological activity. They often show a wide range of pharmacological properties including anti-inflammatory, antimicrobial, and anticancer activities.
  • Neuroscience: Due to its structural analogies with neurotransmitters, 3-pyrrolidin-2-yl-1H-indole may influence neurological functions and is of interest in the study of neurodegenerative diseases.
  • Synthetic Pathways: The synthesis of this compound often involves innovative methods in organic chemistry, paving the way for the development of new synthetic techniques and reactions.

Application Areas

  • Pharmaceutical Development: With its potential therapeutic effects, this compound is being explored for the development of new medications.
  • Chemical Research: It serves as a building block in the synthesis of more complex molecules, showcasing its versatility in drug design.
  • Material Science: Research into its properties may lead to advancements in organic electronics and polymers.

In conclusion, 3-pyrrolidin-2-yl-1H-indole is more than just a compound; it represents a nexus of scientific inquiry and potential application. As researchers continue to unravel its properties, this molecule may play a pivotal role in the future of pharmacology and materials science.

Synonyms
3-(2-pyrrolidinyl)-1H-indole
108-476-2
3-(pyrrolidin-2-yl)-1H-indole
3766-03-8
3-pyrrolidin-2-yl-1H-indole
3-(2-Pyrrolidinyl)indole
BRN 0152014
INDOLE, 3-(2-PYRROLIDINYL)-
DTXSID10958700
BBL021228
STK893934
AKOS005143746
BS-27992
DB-069583
CS-0206255
EN300-1855734