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Coumarin

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Identification
Molecular formula
C9H6O2
CAS number
91-64-5
IUPAC name
3-(pyrrolidine-1-carbonyl)chromen-2-one
State
State

At room temperature, coumarin is generally found in a solid state, often appearing as needle-like crystals or crystalline powder.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.00
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.00
General information
Molecular weight
146.15g/mol
Molar mass
146.1500g/mol
Density
1.3260g/cm3
Appearence

Coumarin appears as a colorless crystalline solid with a sweet, pleasant odor reminiscent of vanillin and freshly-mown hay. It is often used as a fragrance and flavoring agent due to its aromatic properties.

Comment on solubility

Solubility of 3-(pyrrolidine-1-carbonyl)chromen-2-one

The solubility of 3-(pyrrolidine-1-carbonyl)chromen-2-one can be an intriguing topic of study due to its unique structural features. As a derivative of chromen-2-one, which is known for its aromatic stability, the solubility characteristics are influenced by multiple factors:

  • Polarity: The presence of the pyrrolidine ring contributes to the overall polarity of the compound. Increased polarity usually enhances solubility in polar solvents.
  • Hydrogen Bonding: The carbonyl group in the pyrrolidine moiety may engage in hydrogen bonding with potential solvent molecules, facilitating solubility in specific conditions.
  • Solvent Compatibility: Generally, this compound may display better solubility in solvents such as ethanol or DMF, while showing limited solubility in non-polar solvents like hexane.

It is important to note that solubility is highly context-dependent. Factors such as temperature, solvent characteristics, and concentration play significant roles in how well this compound can dissolve. In practical applications, ensuring the use of the correct solvent can significantly affect the effectiveness of the compound.

As you explore the properties of 3-(pyrrolidine-1-carbonyl)chromen-2-one, remember the adage: "The right solvent can make all the difference."

Interesting facts

Interesting Facts about 3-(pyrrolidine-1-carbonyl)chromen-2-one

3-(pyrrolidine-1-carbonyl)chromen-2-one is a fascinating compound that exemplifies the intersection of organic chemistry and medicinal applications. Below are some key insights into this intriguing molecule:

  • Unique Structure: This compound features a chromen-2-one backbone, which is part of the broader flavonoid family, known for their diverse biological activities.
  • Biological Relevance: Chromones, the core structure of this compound, have been studied for their potential anti-inflammatory, antioxidant, and antimicrobial properties. The incorporation of a pyrrolidine group may enhance these effects.
  • Drug Discovery: Compounds like 3-(pyrrolidine-1-carbonyl)chromen-2-one are of great interest in pharmaceutical research. They are often investigated for their potential in developing new therapeutic agents.
  • Potential Applications: Preliminary studies suggest that derivatives from the chromenone family may have applications in cancer treatment, neurological disorders, and metabolic diseases.
  • Synthesis Complexity: The synthesis of this compound usually involves multi-step processes that may require the use of various reagents and conditions, showcasing the creativity required in modern organic synthesis.

As the scientific community continues to explore and uncover the properties of 3-(pyrrolidine-1-carbonyl)chromen-2-one, it stands as a testament to the exciting potential that lies within the realm of chemistry and its applications in real-world challenges.

Synonyms
18144-50-8
COUMARIN, 3-(1-PYRROLIDINYLCARBONYL)-
3-(1-Pyrrolidinylcarbonyl)coumarin
3-Coumarincarbonyl pyrrolidide
BRN 1319093
DTXSID80171146
5-20-01-00486 (Beilstein Handbook Reference)
DTXCID0093637
3-(pyrrolidine-1-carbonyl)-2H-chromen-2-one
3-(pyrrolidine-1-carbonyl)chromen-2-one
2H-1-Benzopyran-2-one, 3-(1-pyrrolidinylcarbonyl)-
CBMicro_031047
MixCom6_001351
Oprea1_080147
MLS000061479
CHEMBL1706669
HMS1690B21
HMS2342H12
STK401572
3-(pyrrolidinylcarbonyl)chromen-2-one
AKOS000602752
UPCMLD0ENAT5575653:001
SMR000070658
BIM-0031104.P001
ST50026224
3-(1-pyrrolidinylcarbonyl)-2H-chromen-2-one
3-(pyrrolidin-1-ylcarbonyl)-2H-chromen-2-one
Z31480690