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Indolequinoline

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Identification
Molecular formula
C17H20N2
CAS number
.
IUPAC name
3-(quinuclidin-2-ylmethyl)-1H-indole
State
State

Indolequinoline is typically found as a solid at room temperature, indicating a crystalline or powder form depending on its purity and preparation process.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
535.00
Boiling point (Kelvin)
808.15
General information
Molecular weight
250.34g/mol
Molar mass
250.3400g/mol
Density
1.2100g/cm3
Appearence

The compound typically appears as a solid at room temperature. It may be available in the form of powder or crystalline structures, depending on specific synthesis and purification methods used.

Comment on solubility

Solubility of 3-(quinuclidin-2-ylmethyl)-1H-indole

The solubility of 3-(quinuclidin-2-ylmethyl)-1H-indole is influenced by several factors, given its complex structure. Understanding its solubility behavior can be enhanced by considering the following key points:

  • Polarity: The presence of both indole and quinuclidine moieties suggests a potential for varied polarity, which could affect how well it dissolves in different solvents.
  • Solvent Effects: Typically, compounds containing polar functional groups tend to be more soluble in polar solvents (like water) and less soluble in non-polar solvents (like hexane).
  • Hydrogen Bonding: The capacity for hydrogen bonding must be recognized, as it may enhance solubility in polar solvents but could also lead to crystallization in specific conditions.
  • pH Dependence: The solubility may vary with changes in pH, particularly if the compound can be protonated or deprotonated, altering its overall charge and solubility characteristics.

In summary, 3-(quinuclidin-2-ylmethyl)-1H-indole exhibits variable solubility based on its structure, polarity, and the nature of the solvent. Exploring these interactions not only highlights the complexity of its solubility behavior but also underlines the necessity for careful selection of solvents in practical applications.

Interesting facts

Exploring 3-(quinuclidin-2-ylmethyl)-1H-indole

3-(quinuclidin-2-ylmethyl)-1H-indole, a compound that draws attention for its complex structure and potential applications in various fields, particularly in medicinal chemistry. Here are some fascinating insights:

  • Structural Diversity: The compound features a unique combination of an indole ring and a quinuclidine moiety, making it an interesting subject for synthetic chemists. This diversity in structure might result in diverse biological activities.
  • Biological Interest: Compounds related to indoles are known for their wide range of biological properties, including pharmacological effects. As a result, 3-(quinuclidin-2-ylmethyl)-1H-indole could exhibit potential therapeutic effects.
  • Research Applications: The indole scaffold plays a crucial role in many natural products and drugs. Its incorporation with other chemical structures can lead to novel compounds that advance our understanding of pharmacology.
  • Potential as a Ligand: The quinuclidine part of the structure may function as a ligand, suggesting that this compound can interact with various receptors or enzymes in biochemical pathways.
  • Odor and Flavor: Some derivatives of indole are known for their aromatic properties. While the compound itself may not be directly associated with fragrance, it belongs to a class of compounds that influence the scent profiles of various products.

In summary, 3-(quinuclidin-2-ylmethyl)-1H-indole stands out not only for its structural characteristics but also for its potential roles in pharmacology and organic synthesis. As we continue to explore compounds like this, we may uncover new pathways for drug development and therapeutic applications.

Synonyms
2-Skatylquinuclidine
BRN 0796326
INDOLE, 3-(2-QUINUCLIDINYLMETHYL)-
5697-99-4
5-23-08-00170 (Beilstein Handbook Reference)
2-(3-indolylmethyl)quinuclidine
DTXSID60972436
3-[(1-Azabicyclo[2.2.2]octan-2-yl)methyl]-1H-indole