Interesting facts
Exploring 3-(Trifluoromethyl)aniline
3-(Trifluoromethyl)aniline is a fascinating compound that captures the interest of organic chemists and material scientists alike. This aromatic amine is characterized by the presence of a trifluoromethyl group, which significantly influences its chemical behavior and properties. Here are some intriguing facts about this compound:
- Unique Substituent: The trifluoromethyl group (–CF3) is renowned for its ability to enhance the lipophilicity of compounds, which can lead to increased bioavailability in pharmaceutical applications.
- Reaction Versatility: 3-(Trifluoromethyl)aniline is known for its reactivity in various organic transformations, including nucleophilic aromatic substitution and coupling reactions, making it a valuable intermediate in the synthesis of dyes, agrochemicals, and pharmaceuticals.
- Environmental Considerations: Given the potential environmental impact of fluorinated compounds, research into the degradation pathways and ecological effects of 3-(trifluoromethyl)aniline is a growing concern, highlighting the critical balance between utility and sustainability.
- Applications in Electronics: The compound finds applications in the burgeoning field of organic electronics, where it can serve as a building block for materials used in organic light-emitting diodes (OLEDs) and organic photovoltaics.
Overall, 3-(Trifluoromethyl)aniline is more than just a chemical compound; it is a gateway to exploring innovative solutions in modern chemistry and technology. As you delve into its study, remember: "Every compound holds secrets waiting to be uncovered."
Synonyms
3-(Trifluoromethyl)aniline
3-Aminobenzotrifluoride
98-16-8
m-Aminobenzotrifluoride
3-Trifluoromethylaniline
Benzenamine, 3-(trifluoromethyl)-
m-Trifluoromethylaniline
3-(Trifluoromethyl)benzenamine
M-(TRIFLUOROMETHYL)ANILINE
m-Aminobenzal fluoride
m-Abtf
3-Trifluoromethyl aniline
alpha,alpha,alpha-Trifluoro-m-toluidine
USAF MA-4
1-Amino-3-(trifluoromethyl)benzene
3-(trifluoromethyl)phenylamine
3-Trifluromethylaniline
CCRIS 2812
3-Amino-a,a,a-trifluorotoluene
HSDB 4249
UNII-Z1RWM538YN
NSC 4540
EINECS 202-643-4
MFCD00007797
UN2948
BRN 0387672
3trifluoromethylaniline
DTXSID9024512
AI3-07422
3-aminobenzo-trifluoride
NSC-4540
3(trifluoromethyl)aniline
3-Aminotrifluorotoluene
Z1RWM538YN
DTXCID504512
3-(trifluoromethyl)-benzenamine
.alpha.,.alpha.,.alpha.-Trifluoro-m-toluidine
EC 202-643-4
4-12-00-01843 (Beilstein Handbook Reference)
UN 2948
M-(TRIFLUOROMETHYL)ANILINE [HSDB]
FLUTAMIDE IMPURITY D [EP IMPURITY]
aniline, 3-trifluoromethyl-
m-Amino-.alpha.,.alpha.,.alpha.-trifluorotoluene
m-Toluidine, .alpha.,.alpha.,.alpha.-trifluoro-
3-AMINO,ALPHA,ALPHA,ALPHA-TRIFLUORO-TOLUENE
AMINO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE, 3-
Toluene, 3-amino-.alpha.,.alpha.,.alpha.-trifluoro-,
3-AMINO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUOROTOLUENE
CAS-98-16-8
3-Trifluoromethyl-phenylamine
FLUTAMIDE IMPURITY D (EP IMPURITY)
3-(trifluoromethyl)-aniline
3-(Trifluoromethyl) aniline
m-Amino-alpha,alpha,alpha-trifluorotoluene
m-Toluidine, alpha,alpha,alpha-trifluoro-
Toluene, 3-amino-alpha,alpha,alpha-trifluoro-
Flutamide Imp. D (EP); Niflumic Acid Imp. C (EP); 3-(Trifluoromethyl)aniline; Flutamide Impurity D; Niflumic Acid Impurity C
mAminobenzal fluoride
mAminobenzotrifluoride
MABTF
3Aminobenzotrifluoride
3-aminobenzotriflouride
3-trifluormethylaniline
3-trifluoromethylanilin
3trifluoromethyl aniline
3-amino-benzotrifluoride
3-trifloromethyl aniline
m-trifluoromethyl aniline
m-trifluoromethyl-aniline
meta-aminobenzotrifluoride
3-trifluoromethyl-aniline
5-trifluoromethyl-aniline
3-(trifluormethyl)aniline
meta-trifluoromethylaniline
3-(tri-fluormethyl)aniline
3-(trifluor-methyl)aniline
3-Trifluoromethylbenzenamine
3-trifluoromethylphenylamine
3-(trifluoro-methyl)aniline
3-trifluoromethylbenzeneamine
SCHEMBL39591
3(Trifluoromethyl)benzenamine
3-trifluoromethyl phenyl amine
1Amino3(trifluoromethyl)benzene
3-(trifluoromethyl)benzeneamine
3-F3CC6H4NH2
Benzenamine, 3(trifluoromethyl)
3-(trifluoromethyl)benzenaminium
CHEMBL1162293
[3-(trifluoromethyl)phenyl]amine
NSC4540
ISKCXMWFGFWNBA-UHFFFAOYSA-N
XNZIQYHXPBHLRA-UHFFFAOYSA-N
alpha,alpha,alphaTrifluoromtoluidine
2,3,6-trifluoro-5-methyl-aniline
CS-D1197
Tox21_201909
Tox21_303081
AC-027
STK943763
2,4,6-trifluoro-3-methylbenzenamine
3-(Trifluoromethyl)aniline, >=99%
mToluidine, alpha,alpha,alphatrifluoro
Toluene,.alpha.,.alpha.-trifluoro-,
AKOS000119177
mAminoalpha,alpha,alphatrifluorotoluene
.alpha.,.alpha.-Trifluoro-m-toluidine
FA36984
PS-8763
NCGC00091738-01
NCGC00091738-02
NCGC00091738-03
NCGC00257044-01
NCGC00259458-01
Toluene, 3aminoalpha,alpha,alphatrifluoro
alpha, alpha, alpha-trifluoro-m-toluidine
m-Amino-.alpha.,.alpha.-trifluorotoluene
A0434
NS00004089
EN300-19104
3-Trifluoromethylaniline [UN2948] [Poison]
Toluene, 3-amino-alpha,alpha,alpha-trifluoro-,
3-AMINO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE
A935951
AG-617/02198031
AH-357/04334061
M-AMINO-ALPHA,ALPHA, ALPHA-TRIFLUOROTOLUENE
Q424934
3-aminobenzotrifluoride / 3-(trifluoromethyl)aniline
F2190-0435
Z104472788
51R
Solubility of 3-(trifluoromethyl)aniline
3-(Trifluoromethyl)aniline is a fascinating compound when it comes to its solubility characteristics. This aromatic amine, featuring a trifluoromethyl group, exhibits unique behaviors in different solvents.
Key Factors Affecting Solubility:
In summary, the solubility of 3-(trifluoromethyl)aniline is influenced by the interplay of its molecular structure and the nature of the solvent. Generally, it is soluble in organic solvents while exhibiting limited solubility in polar protic solvents such as water. Understanding these solubility dynamics can provide insights into its applications and behavior in various chemical environments.