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Doxorubicin

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Identification
Molecular formula
C27H29NO11
CAS number
23214-92-8
IUPAC name
30-oxo-19-oxa-2,6,10,12-tetrazahexacyclo[18.6.2.12,5.114,18.08,12.023,27]triaconta-1(26),8,10,14(29),15,17,20(28),21,23(27),24-decaene-17-carbonitrile
State
State

At room temperature, doxorubicin is found as a solid.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
785.00
Boiling point (Kelvin)
1 058.15
General information
Molecular weight
543.53g/mol
Molar mass
543.5250g/mol
Density
1.6000g/cm3
Appearence

Doxorubicin is typically observed as a red-orange crystalline solid.

Comment on solubility

Solubility of 30-oxo-19-oxa-2,6,10,12-tetrazahexacyclo[18.6.2.12,5.114,18.08,12.023,27]triaconta-1(26),8,10,14(29),15,17,20(28),21,23(27),24-decaene-17-carbonitrile (C27H29NO11)

The solubility of the compound 30-oxo-19-oxa-2,6,10,12-tetrazahexacyclo[18.6.2.12,5.114,18.08,12.023,27]triaconta-1(26),8,10,14(29),15,17,20(28),21,23(27),24-decaene-17-carbonitrile is influenced by various factors, including its complex structure and functional groups.

Key aspects of its solubility include:

  • Polarity: This compound has multiple nitrogen and oxygen atoms, which can contribute to polarity, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: The presence of nitrogens may allow for hydrogen bonding with solvents, leading to increased solubility.
  • Hydrophobic Regions: The large hydrocarbon section can hinder solubility in highly polar solvents, suggesting that it may perform better in organic solvents.
  • Temperature Dependency: Solubility may vary with temperature; increasing temperatures often increase solubility for organic compounds.

In general, predictions about solubility for such a complex molecule are not straightforward and may require empirical testing. As noted in the literature, "The intricate interplay of hydrophilic and hydrophobic characteristics can significantly impact solubility behavior."

For practical applications, conducting solubility tests in various solvents is essential to ascertain the most effective solvent to use.

Interesting facts

Fascinating Insights into 30-oxo-19-oxa-2,6,10,12-tetrazahexacyclo[18.6.2.12,5.114,18.08,12.023,27]triaconta-1(26),8,10,14(29),15,17,20(28),21,23(27),24-decaene-17-carbonitrile

The compound 30-oxo-19-oxa-2,6,10,12-tetrazahexacyclo[18.6.2.12,5.114,18.08,12.023,27]triaconta-1(26),8,10,14(29),15,17,20(28),21,23(27),24-decaene-17-carbonitrile is a striking example of complex organic chemistry, showcasing the intricate relationship between structure and function in molecular design.

Key Characteristics:

  • Cyclic Structure: This compound contains a unique arrangement of cyclic and acyclic frameworks, which enhances its stability and reactivity.
  • Multi-Nitrogen Atoms: The presence of multiple nitrogen atoms contributes to its potential applications in catalysis and as a ligand in coordination chemistry.
  • Oxygen-Containing Heterocycles: The incorporation of oxygen in the ring system aids in enhancing solubility and influencing the electronic properties.

Moreover, compounds such as this one can play a significant role in various fields:

  • Medicinal Chemistry: Compounds with similar frameworks have shown potential in drug development, particularly as anticancer agents or antibiotics.
  • Material Science: The structural complexity may allow for the design of novel materials with specific electronic or optical properties.
  • Biochemistry: Understanding how such compounds interact with biological systems can lead to advancements in therapeutic strategies.

A compelling aspect of this compound is its systematic nomenclature, which reflects the detailed composition and schematic of its carbon skeleton and functional groups. As chemistry continues to evolve, such intricate compounds illustrate the endless possibilities for molecular synthesis and the expansion of our understanding in the field.

In the words of renowned chemist Linus Pauling, "Chemistry is the science of substances, their compositions, structures, properties, and the changes they undergo." Through the exploration of such compounds, we uncover the profound complexities of chemical substance interactions in nature.

Synonyms
1ld8
COMPOUND 49
PD036027
AZA-CYCLOOCTADECOSINE-9-CARBONITRILE
(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI
(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI AZA-CYCLOOCTADECOSINE-9-CARBONITRILE
(5R)-30-oxo-19-oxa-2,6,10,12-tetraazahexacyclo[18.6.2.1~2,5~.1~14,18~.0~8,12~.0~23,27~]triaconta-1(27),8,10,14(29),15,17,20(28),21,23,25-decaene-17-carbonitrile (non-preferred name)
U49