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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
33-(4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
State
State

At room temperature, erythromycin exists as a crystalline solid.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.00
Boiling point (Celsius)
619.00
Boiling point (Kelvin)
892.00
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2461g/cm3
Appearence

Erythromycin is typically a white or slightly yellow, odorless, crystalline powder. It can deteriorate when exposed to light and it may appear as a crystalline solid when isolated.

Comment on solubility

Solubility of 33-(4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid (C37H67NO13)

The solubility of complex organic compounds like C37H67NO13 can vary widely and is influenced by several factors. Understanding the solubility characteristics of this compound aids in its practical applications:

  • Polarity: Due to its multiple hydroxyl (-OH) groups, this compound may exhibit moderate to high polarity, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of amino and hydroxyl groups facilitates strong hydrogen bonding with solvent molecules, contributing positively to solubility in water and alcohols.
  • Hydrophobic Regions: With a significant hydrophobic carbon framework, solubility in non-polar solvents, such as hexane or toluene, is likely to be limited.
  • pH Dependence: Solubility could also be affected by the pH of the solution, especially due to the presence of carboxylic acid functional groups, which may ionize under alkaline conditions.

In essence, C37H67NO13 is expected to show enhanced solubility in polar solvents while demonstrating limited solubility in non-polar solvents. Additionally, factors like temperature and the presence of other solutes can further impact its solubility profile.

Interesting facts

Interesting Facts about 33-(4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid

This fascinating compound is an intricate tapestry of chemical structures and functionalities. Below are some notable aspects that showcase its uniqueness:

  • Complex Structure: The compound features a bicyclic nonatriaconta structure, which is quite rare among organic compounds. Its elaborate arrangement of multiple hydroxyl groups and a carboxylic acid moiety significantly contributes to its chemical behavior.
  • Biological Relevance: Compounds with large polyhydroxylated systems are often investigated for their potential pharmacological properties. This compound could exhibit intriguing interactions with biological systems, influencing various biochemical pathways.
  • Natural Occurrence: While this compound’s exact source may not be well-documented, many similar compounds are derived from natural sources such as plants and fungi, hinting at potential applications in natural product synthesis and pharmacognosy.
  • Research Applications: With its ability to form multiple hydrogen bonds due to its hydroxyl groups, this compound may serve as a model for studying molecular recognition and self-assembly, important concepts in supramolecular chemistry.
  • Potential in Material Science: The unique configurations present in this compound can inspire innovative materials, particularly in areas like nanotechnology and polymer science, where multifunctional properties are crucial.

As scientists continue to explore the capabilities of intricate organic molecules like this one, they open doors to new discoveries in chemistry, biology, and materials science. The pursuit of understanding such compounds not only enriches our knowledge but also aids in the advancement of technology and medicine.

Synonyms
1397-89-3
Ambisome
MLS002702966
SMR001566780
33-[(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
NSC527017
33-((3-amino-3,6-dideoxyhexopyranosyl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
33-[(3-Amino-3,6-dideoxyhexopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
cid_1972
CHEMBL1700818
SCHEMBL17976509
BDBM83198
DTXSID60859632
Amphotericin B from Streptomyces species
SY060712