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Cloxacillin

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Identification
Molecular formula
C19H18ClN3O5S
CAS number
61-72-3
IUPAC name
3,3-dimethyl-6-[[2-(methylamino)-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

Cloxacillin, at room temperature, is in the form of a solid crystalline powder. It is stable under normal conditions but should be handled and stored properly to maintain its efficacy.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
305.90
Boiling point (Kelvin)
579.05
General information
Molecular weight
435.89g/mol
Molar mass
435.9160g/mol
Density
1.3300g/cm3
Appearence
Cloxacillin typically appears as a white to off-white powder. It might be odorless or possess a faint odor specific to penicillins.
Comment on solubility

Solubility Characteristics of 3,3-Dimethyl-6-[[2-(methylamino)-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

The solubility of complex organic compounds, such as 3,3-dimethyl-6-[[2-(methylamino)-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, can be influenced by several factors. Here are some key points to consider:

  • Polarity: The presence of polar functional groups like amino and carboxylic acid can enhance solubility in polar solvents, particularly in water.
  • Hydrogen Bonding: Compounds that can donate or accept hydrogen bonds (e.g., due to -NH or -COOH groups) often exhibit increased solubility due to stronger interactions with solvent molecules.
  • Structural Complexity: The bicyclic structure and substituents may create steric hindrance, potentially reducing solubility in certain organic solvents.
  • pH Dependence: The solubility may vary with pH because the ionization of the carboxylic acid group can alter its solubility in aqueous solutions.

Overall, while general trends can help predict solubility, the specific behaviors of such a complex chemical compound may still require experimental determination. Developing a thorough understanding of its solubility profile is essential for various applications, especially in pharmaceutical contexts where bioavailability is crucial.

Interesting facts

Interesting Facts about 3,3-dimethyl-6-[[2-(methylamino)-2-phenyl-acetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound is a fascinating example of a complex organic molecule known for its potential biological activity. Here are some intriguing highlights:

  • Structural Complexity: The compound features a unique bicyclic framework, which is essential in drug design, as it often leads to increased potency and selectivity in biological systems.
  • Pharmacological Interest: Often represented in studies looking into its ability to mimic natural hormones or neurotransmitters, this compound may play a role in various physiological processes.
  • Thiazolidine Skeleton: The integration of thia (sulfur) and nitrogen in the bicyclic structure enhances its pharmaceutical properties, potentially offering novel paths for antibiotic or analgesic development.
  • Amine Substitution: The presence of a methylamine group can significantly influence the compound's interaction with biological targets, making it a subject of interest in medicinal chemistry.

As described by chemists, "the more complex the structure, the greater the potential for engaging with biological systems in innovative ways." This underscores the importance of compounds like this in the ongoing search for new therapeutic agents.

Furthermore, its intricate design not only reflects the elegance of organic synthesis but also opens avenues for synthesizing derivatives that might enhance its efficacy. Various modifications to its structure can lead to a diverse pharmacological profile, making it an exciting subject for research in drug development.

Synonyms
SCHEMBL13791321